The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Back pain (up to 4%)
- Constipation (up to 4%)
- Muscle pain (up to 3%)
- Diarrhea (up to 3%)
- Pain in arm or leg (up to 2%)
Zypitamag serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Severe muscle damage (rhabdomyolysis): severe muscle weakness or pain, dark brown urine, fever, extreme tiredness
- Liver problems: swelling of your stomach, yellowing of your skin or the whites of your eyes, dark or brown urine, confusion
Source: DailyMed
More on Zypitamag side effects

The following Zypitamag side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Less common
Difficulty with moving
joint pain
muscle ache, cramp, pain, or stiffness
pain in the arms and legs
swollen joints
Incidence not known
Chills
clay-colored stools
dark urine
difficulty breathing
dizziness
general feeling of discomfort or illness
headache
hives or welts, itching skin, or rash
loss of appetite
shivering
stomach pain
sweating
trouble sleeping
unusual tiredness or weakness
vomiting
vomiting of blood
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
Burning, numbness, tingling, or painful sensations
decreased interest in sexual intercourse
discouragement
feeling sad or empty
inability to have or keep an erection
irritability
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
loss in sexual ability, desire, drive, or performance
loss of interest or pleasure
loss of memory
problems with memory
redness of the skin
trouble concentrating
unsteadiness or awkwardness
weakness in the arms, hands, legs, or feet
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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