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Zypitamag

Zypitamag Side Effects

Robert Chad Hakim, PharmD, BCCCPCydnee Ng, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Cydnee Ng, PharmD
Last reviewed on March 5, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Back pain (up to 4%)
  • Constipation (up to 4%)
  • Muscle pain (up to 3%)
  • Diarrhea (up to 3%)
  • Pain in arm or leg (up to 2%)

Zypitamag serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Severe muscle damage (rhabdomyolysis): severe muscle weakness or pain, dark brown urine, fever, extreme tiredness
  • Liver problems: swelling of your stomach, yellowing of your skin or the whites of your eyes, dark or brown urine, confusion
When do Zypitamag possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Risk of muscle pain
Risk of back pain
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

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The following Zypitamag side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Difficulty with moving

joint pain

muscle ache, cramp, pain, or stiffness

pain in the arms and legs

swollen joints

Incidence not known

Chills

clay-colored stools

cough

dark urine

diarrhea

difficulty breathing

dizziness

fever

general feeling of discomfort or illness

headache

hives or welts, itching skin, or rash

loss of appetite

muscle spasm

nausea

runny nose

shivering

sore throat

stomach pain

sweating

trouble sleeping

unusual tiredness or weakness

vomiting

vomiting of blood

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Back pain

difficulty having a bowel movement

Incidence not known

Burning, numbness, tingling, or painful sensations

decreased interest in sexual intercourse

discouragement

feeling sad or empty

inability to have or keep an erection

irritability

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

loss in sexual ability, desire, drive, or performance

loss of interest or pleasure

loss of memory

problems with memory

redness of the skin

trouble concentrating

unsteadiness or awkwardness

weakness in the arms, hands, legs, or feet

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Cydnee Ng, PharmD
Reviewed by:
Cydnee Ng, PharmD
Cydnee Ng, PharmD, is a drug information pharmacist at GoodRx, where she lends her expertise to providing reader-friendly, accessible content about medications. She holds her pharmacist license in California.

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