Key takeaways:
Trokendi XR (topiramate ER) is a prescription-only medication that’s FDA approved to treat seizures in adults and children. It can also be used for migraine prevention.
Insurance coverage for Trokendi XR varies widely by plan type, with Medicaid covering the highest percentage of enrollees.
Without insurance, 30 capsules of Trokendi XR 100 mg cost an average of $1150.73. If you qualify for the manufacturer’s copay savings card, you may pay as little as $0 per month for your prescription.
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Trokendi XR (topiramate ER) is a prescription-only medication used to treat seizures in adults and children ages 6 years and older. It’s also FDA approved to prevent migraines in people as young as 12.
Both brand-name and generic versions of Trokendi XR are available. The medication comes as an extended-release capsule that you take once a day. Most people start with a low dosage, which is slowly increased each week until a regular maintenance dosage is reached. Your exact dosage will depend on the condition being treated.
Trokendi XR can cost hundreds of dollars to over $1,000 a month without insurance or discounts. But you may be able to reduce the cost of your prescription with a GoodRx coupon or a manufacturer’s copay savings program.
How much does Trokendi XR cost?
Without insurance or discounts, 30 capsules of Trokendi XR 100 mg cost an average of $1150.73. The generic version costs an average of $808.61 for the same quantity, form, and dose. This quantity would last 1 month if you’re taking the recommended maintenance dosage of 100 mg once daily to prevent migraines.
For seizure treatment, a commonly recommended maintenance dosage is 400 mg once daily. In this case, a 30-day supply — or 60 capsules of Trokendi XR 200 mg — costs an average of $3126.07. But you may pay about $1988.81 for the same quantity, form, and dose of the generic version.
Here are the average retail prices for various quantities and doses of brand-name and generic Trokendi XR capsules.
Trokendi XR version | Quantity and form | Dose | Average retail price |
|---|---|---|---|
Brand name | 30 capsules | 25 mg | |
Brand name | 30 capsules | 50 mg | |
Brand name | 30 capsules | 100 mg | |
Brand name | 30 capsules | 200 mg | |
Brand name | 60 capsules | 200 mg | |
Generic | 30 capsules | 25 mg | |
Generic | 30 capsules | 50 mg | |
Generic | 30 capsules | 100 mg | |
Generic | 30 capsules | 200 mg | |
Generic | 60 capsules | 200 mg |
What factors affect the cost of Trokendi XR?
Factors that can affect the cost of Trokendi XR include:
Location: Prices for prescription medications can vary by region. GoodRx research shows that someone in Denver may pay less for prescription medications than someone in New Orleans, for example.
Pharmacy: Pharmacies can charge different prices for prescription medications.
Insurance: If you have an insurance plan that covers Trokendi XR, you may still have to pay a deductible and copays or coinsurance.
Dosage: Your prescribed dosage can affect your overall cost. For adults, the prescribed dosage depends on age, the condition being treated, and what other medications are being taken. For children and teens ages 6 to 16, the dosage is generally based on body weight.
Generic vs. brand name: Choosing the generic version instead of the brand-name version can result in significant savings.
Discounts: You may be able to pay less for Trokendi XR if you qualify for the manufacturer’s copay savings card or use a discount program.
Does insurance cover Trokendi XR?
Nearly half of the people enrolled in Affordable Care Act (ACA, also known as Obamacare) marketplace plans have coverage for Trokendi XR. More than 2 in 5 ACA plans require prior authorization, and roughly 1 in 3 require enrollees to try other medications first (a process known as step therapy).
About 3 in 4 people with commercial insurance plans have access to coverage for Trokendi XR. Some enrollees will need to get prior authorization, and step therapy is required for about one-third.
Medicare plans rarely cover Trokendi XR. Nearly everyone enrolled in Medicaid has coverage for Trokendi XR, but there’s a high likelihood that prior authorization will be needed. And many Medicaid enrollees are subject to step therapy requirements.
Find out more about your coverage and any approval requirements by reviewing your plan’s formulary (list of covered medications) or calling your insurance company.
Save money on medication costs. Here are several ways to lower your prescription medication costs.
Can you pay for Trokendi XR (topiramate ER) with your HSA? See how to use your health savings account (HSA) to cover Trokendi XR and other eligible expenses.
Wondering about side effects? From pins and needles to drowsiness, here are some topiramate side effects to watch for.
How different insurance plans cover Trokendi XR
The table below breaks down the percentage of enrollees who have coverage for Trokendi XR by insurance type. It also shows the likelihood of having prior authorization and step therapy requirements.
Insurance type | Enrollees covered for Trokendi XR 100 mg | Enrollees required to get prior authorization | Enrollees required to do step therapy |
|---|---|---|---|
48.4% | 44% | 34.8% | |
Commercial plans (excluding ACA plans) | 73.6% | 25.2% | 33.2% |
Medicare, including original Medicare and Medicare Advantage plans | 5.9% | 5.6% | 2.6% |
Medicaid, including state-run and managed care plans | 99.8% | 76.3% | 36.8% |
Source: Managed Markets Insight & Technology, LLC™, as of June 13, 2025. (See methodology below.)
If your insurance doesn’t cover Trokendi XR, consider taking the following steps:
Check if you’re eligible for the manufacturer’s copay savings card (details below).
Discuss other migraine prevention medications or antiepileptics with your prescriber. And ask about the generic version of Trokendi XR.
Request a formulary exception to get Trokendi XR covered by your plan. Your prescriber will likely need to write a letter of medical necessity explaining why Trokendi XR is required for your condition. You can appeal the decision if the request is denied.
Compare health plans during the next open enrollment period. You might find a plan that better covers your medications with lower out-of-pocket costs.
Ways to save on Trokendi XR
Trokendi XR can cost hundreds to over $1,000 monthly without insurance coverage. But reducing your out-of-pocket expenses or even getting the medication for free is possible with the eight strategies below.
1. Use a GoodRx coupon
GoodRx offers free coupons that can lower the cost of generic or brand-name Trokendi XR at many pharmacies. Here’s what you might pay for your prescription using a GoodRx coupon.
Trokendi XR version | Quantity and form | Dose | GoodRx price |
|---|---|---|---|
Brand name | 30 capsules | 25 mg | |
Brand name | 30 capsules | 50 mg | |
Brand name | 30 capsules | 100 mg | |
Brand name | 30 capsules | 200 mg | |
Brand name | 60 capsules | 200 mg | |
Generic | 30 capsules | 25 mg | |
Generic | 30 capsules | 50 mg | |
Generic | 30 capsules | 100 mg | |
Generic | 30 capsules | 200 mg | |
Generic | 60 capsules | 200 mg |
Get a coupon by visiting www.goodrx.com or downloading the GoodRx app.
2. See if you qualify for the manufacturer’s copay savings program
If you qualify for the Trokendi XR copay savings card, you could pay as little as $0 per month for your prescription.
To be eligible, you must:
Not be enrolled in Medicaid, Medicare, or another federal or state health insurance program
Have commercial insurance or pay cash for your prescription
Have a valid prescription for Trokendi XR
3. Apply for the Supernus Support patient assistance program
The Supernus Support patient assistance program provides Trokendi XR at no cost to qualified people who can’t afford the medication.
To qualify, you must:
Be uninsured or underinsured
Meet specific income requirements
Have a valid prescription for Trokendi XR
To apply, your prescriber must fill out and submit the enrollment form. A Supernus Support representative will work with you to determine your eligibility and, if you’re approved, connect you with a designated pharmacy that provides the medication.
4. Compare prices at different pharmacies
The cost of Trokendi XR can vary widely from one pharmacy to another. Before filling your prescription, check prices at a few local pharmacies.
You can also use the GoodRx website or app to quickly and easily compare prices online. Many people save money simply by choosing a different pharmacy.
5. Ask about the generic version
Generic topiramate ER generally costs less than brand-name Trokendi XR. Ask your prescriber about switching to the generic version.
6. Try the Patient Advocate Foundation Co-Pay Relief Program
The Patient Advocate Foundation Co-Pay Relief Program helps cover various out-of-pocket medical expenses for qualifying individuals. When available, the program may provide assistance of up to $2,000 per year for migraine treatment and up to $3,000 per year for epilepsy treatment. You must meet income and insurance requirements to qualify.
Check the program’s website regularly or sign up for email updates to be notified when funds are available.
7. Request a 90-day supply
Many insurance plans reduce copays for 3-month supplies of medications, and some pharmacies offer bulk discounts if you pay cash. If you have insurance, you might also find additional savings through your plan’s mail-order pharmacy.
To see if you can save with this option, ask your healthcare professional for a 90-day prescription once you’re receiving a stable dose of the medication.
8. Tap into your tax-advantaged healthcare account
Do you have a health savings account (HSA), flexible spending account (FSA), or health reimbursement arrangement (HRA)? If so, you can use the tax-free funds in your account to pay for many healthcare expenses, including prescription medications like Trokendi XR.
HSA funds roll over each year and are available for future expenses. But be sure to use your FSA dollars before they expire, if applicable.
The bottom line
Without insurance, 30 capsules of 100 mg brand-name Trokendi XR (topiramate ER) cost an average of $1150.73. What you actually pay will depend on factors like your pharmacy, location, dosage, and insurance coverage.
If you have commercial insurance, you may qualify for the manufacturer’s copay savings card, which could reduce your costs for Trokendi XR to as little as $0 per month. Other ways to save include using a GoodRx coupon, switching to the generic version, or filling a 90-day supply. You can also use funds from your tax-advantaged healthcare account to help pay for your prescription.
Why trust our experts?
Methodology
We obtained national prescription coverage data for each medication from Managed Markets Insight & Technology (MMIT). The data reflects health insurance coverage as of June 2025.
We calculated the percentage of enrollees in plans that cover each medication by dividing the number of enrollees covered for the medication within a specific insurance channel (e.g., ACA, Medicare, Medicaid) by the total number of enrollees in all plans within that channel.
We determined the percentage of enrollees in plans with a prior authorization requirement by calculating the proportion of enrollees in plans that required prior authorization for the medication within each channel.
Finally, we measured the percentage of enrollees in plans with a step therapy requirement by calculating the proportion of enrollees in plans that imposed step therapy requirements for the medication in each channel.
These estimates, derived from national MMIT coverage data, provide insight into health insurance coverage for each medication. They take into account restrictions such as prior authorization, step therapy, and quantity limits. The percentages are expressed relative to the total number of enrollees covered by various insurance channels, including ACA plans, commercial (excluding ACA) plans, Medicare, and Medicaid (both state-run and managed care plans).
References
HealthCare.gov. (n.d.) Appealing a health plan decision.
Medicaid.gov. (n.d.). Managed care.
Patient Advocate Foundation. (n.d.). Epilepsy.
Patient Advocate Foundation. (n.d.). Migraines.
Teva Pharmaceuticals. (2025). Topiramate capsule, extended release [package insert]. DailyMed.
Trokendi XR. (n.d.). Co-pay savings and support. Supernus Pharmaceuticals.
Trokendi XR. (n.d.). Patient assistance. Supernus Pharmaceuticals.
Trokendi XR. (2020). Supernus Support enrollment form for Trokendi XR. Supernus Pharmaceuticals.
