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Tpoxx

Tecovirimat
Used for Smallpox

Tpoxx (tecovirimat) comes as both an oral capsule and an intravenous (IV) infusion and is approved to treat smallpox in adults and children. This medication is limited in availability because it's reserved for the Strategic National Stockpile. Because of the monkeypox outbreak in the United States, the CDC expanded access to this medication to treat monkeypox in 2022 (although it's not yet FDA-approved for this use). Please note that Tpoxx (tecovirimat) isn't a smallpox vaccine or a monkeypox vaccine, so it can't be used to prevent smallpox or monkeypox.

Reviewed by:Last reviewed on August 8, 2022
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What is Tpoxx (tecovirimat)?

What is Tpoxx (tecovirimat) used for?

  • Treatment of smallpox disease

How Tpoxx (tecovirimat) works

Tpoxx (tecovirimat) is an antiviral medication. It works against the variola virus, the virus that causes smallpox. The medication blocks a viral protein that's important for allowing the variola virus to grow. This stops the virus from spreading in the body.

Drug facts

Common BrandsTpoxx
Drug ClassAntiviral
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
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Avg retail price
$12.99(Save 65.97%)
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$4.42
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Tpoxx (tecovirimat) dosage

The average cost for 28 capsules of 200mg of Tpoxx (tecovirimat) is $4.42 with a free GoodRx coupon. This is 65.97% off the average retail price of $12.99.
capsuleCapsule
DosageQuantityPrice as low asPrice per unit
200mg28 capsules$4.42$0.16

Typical dosage for Tpoxx (tecovirimat)

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