Is chlorthalidone/reserpine still available?

No, chlorthalidone/reserpine has been [discontinued](https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=015103) and is no longer available in the United States. It's not clear why chlorthalidone/reserpine was discontinued.

Regroton

Q: What is chlorthalidone/reserpine?

Chlorthalidone/reserpine is made up of two medications that lower your blood pressure. [__Chlorthalidone__](https://www.goodrx.com/chlorthalidone/what-is) is a thiazide-like diuretic (water pill) that [works in the kidneys](https://www.ncbi.nlm.nih.gov/books/NBK553174/#article-57164.s3) to remove extra water, which lowers blood pressure and gets rid of swelling. [__Reserpine__](https://www.goodrx.com/reserpine/what-is) is a [*Rauwolfia* alkaloid](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566472/) that [works by](https://www.ncbi.nlm.nih.gov/books/NBK557767/#article-28402.s3) lowering the levels of certain chemicals in your body that can raise your blood pressure.

Q: Are there currently available medications that are used in place of chlorthalidone/reserpine?

Yes. [Reserpine](https://www.goodrx.com/reserpine/what-is) as a single-ingredient medication has also been discontinued. But [chlorthalidone](https://www.goodrx.com/chlorthalidone/what-is) on its own and in combination with other medications is still available. There are also other [available medications that work well for treating high blood pressure](https://www.goodrx.com/conditions/hypertension/high-blood-pressure-medications).

chlorthalidone and reserpine

Used for Hypertension

Chlorthalidone/reserpine is a combination medication used to lower blood pressure. It's no longer available in the United States because it was discontinued.

Reviewed by:

Robert Chad Hakim, PharmD, BCCCP

Allison Gourley, PharmD

Last reviewed on June 28, 2022

What is Chlorthalidone/reserpine?

What is Chlorthalidone/reserpine used for?

High blood pressure

Are you looking for information on chlorthalidone alone instead?

Drug facts

Common Brands	Regroton(brand no longer available)
Drug Class	Diuretic / Rauwolfia alkaloid
Controlled Substance Classification	Not a controlled medication
Generic Status	No lower-cost generic available
Availability	Prescription only

Common Brands

Regroton(brand no longer available)

Drug Class

Diuretic / Rauwolfia alkaloid

Controlled Substance Classification

Not a controlled medication

Generic Status

No lower-cost generic available

Availability

Prescription only

Common questions about Regroton

Regroton is made up of two medications that lower your blood pressure. Chlorthalidone is a thiazide-like diuretic (water pill) that works in the kidneys to remove extra water, which lowers blood pressure and gets rid of swelling. Reserpine is a Rauwolfia alkaloid that works by lowering the levels of certain chemicals in your body that can raise your blood pressure.

No, Regroton has been discontinued and is no longer available in the United States. It's not clear why Regroton was discontinued.

Yes. Reserpine as a single-ingredient medication has also been discontinued. But chlorthalidone on its own and in combination with other medications is still available. There are also other available medications that work well for treating high blood pressure.