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Probuphine

buprenorphine
Used for Opioid Dependence, Pain

Probuphine (buprenorphine) is an implant used with counseling and behavioral therapy for long-term treatment of opioid use disorder. It's placed under the skin on the inside of the upper arm by a trained healthcare provider. Probuphine (buprenorphine) has been discontinued and is no longer available in the United States.

Reviewed by:
reviewerSarah Lobello Pearson, PharmD
reviewerDaisy Chau, PharmD
Last reviewed on January 9, 2023
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What is Probuphine (buprenorphine)?

What is Probuphine (buprenorphine) used for?

  • Opioid use disorder (OUD) in people already stable on low-to-medium doses of under-the-tongue buprenorphine

Drug facts

Common BrandsProbuphine(brand no longer available)
Drug ClassOpioid partial agonist
Controlled Substance ClassificationSchedule III
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
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Probuphine (buprenorphine) dosage

Typical dosage for Probuphine (buprenorphine)

References

Best studies we found

Titan Pharmaceuticals, Inc. (2020). Titan Pharmaceuticals provides a strategic & corporate update. PRNewswire.

Titan Pharmaceuticals, Inc. (2021). PROBUPHINE- buprenorphine hydrochloride implant.

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