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Macrilen

macimorelin
Used for Growth Hormone Deficiency
Used for Growth Hormone Deficiency

Macrilen (macimorelin) is a medication used by healthcare providers to test for adult growth hormone deficiency. This is a test to check whether your body makes enough growth hormone (GH). Macrilen (macimorelin) is given as an oral solution that you drink, but you'll need to get several blood draws afterwards to measure your GH levels.

Last reviewed on July 12, 2022
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What is Macrilen (macimorelin)?

What is Macrilen (macimorelin) used for?

  • Diagnosis of adult growth hormone deficiency (AGHD)

How Macrilen (macimorelin) works

Drug Facts

Common BrandsMacrilen
Drug ClassGrowth hormone releasing factor agonist
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
faqs

Frequently asked questions about Macrilen (macimorelin)

What is Macrilen (macimorelin)?
Macrilen (macimorelin) is a medication that your provider gives you to take so they can test to see if you are low on growth hormone (GH). GH is important for proper growth and plays a major role in many processes in your body. In adults, low levels of GH can affect the nerves, brain, heart, muscles, metabolism, and bones. Macrilen (macimorelin) works by telling your body to release more GH.
How do I take Macrilen (macimorelin)?
This medication is an oral solution that you'll drink by mouth. Your provider will prepare and calculate your dose of Macrilen (macimorelin) based on your weight. You'll need to fast for at least 8 hours before drinking Macrilen (macimorelin). On the day of your adult growth hormone deficiency test, you'll drink the Macrilen (macimorelin) solution all at once in 30 seconds. After this, you'll have a series of blood draws done to check your GH levels. Ask your provider for more information on what to expect during your test.
How do I prepare for the test to check for my growth hormone levels?
Make sure you don't eat or drink anything, except for water, for at least 8 hours before your test. Your treatment for GH will need to be stopped at least one week before your test with Macrilen (macimorelin). Discuss with your provider what other medications you need to stop taking in advance. Certain medications (e.g. growth hormone therapy, thyroid medications) can affect your hormones and alter your test results.
How long is the testing process to check for growth hormone levels?
The entire testing process can take at least 2 hours, so please be prepared. Once the Macrilen (macimorelin) solution is given to you, drink the entire amount within 30 seconds. After taking your medication, you will be monitored for the remainder of the test. Your provider will take your blood sample at 30 minutes, 45 minutes, 60 minutes, and 90 minutes after you drink your Macrilen (macimorelin) solution.
What are some side effects of Macrilen (macimorelin)?
Common side effects with Macrilen (macimorelin) include changes in your taste, dizziness, headache, tiredness, nausea, and hunger. Other less common side effects can include diarrhea, feeling hot, and sweating a lot. Though more rare, Macrilen (macimorelin) can also affect your heartbeat and cause a serious heart problem called QT prolongation. Speak with your provider before going in for your test if you are taking other medications that can affect your heart.
Can Macrilen (macimorelin) be given during pregnancy and breastfeeding?
It's not known if Macrilen (macimorelin) can cause harm to your unborn baby or pass into your breastmilk. Speak to your provider if you are pregnant or breastfeeding, and they can help you determine if you can take Macrilen (macimorelin) for your GH deficiency test.
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