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Clotrimazole/Betamethasone

Clotrimazole/Betamethasone Side Effects

Robert Chad Hakim, PharmD, BCCCPDaisy Chau, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Daisy Chau, PharmD
Last reviewed on January 16, 2026

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Tingling or numbness

Less Common Side Effects

  • Rash
  • Swelling
  • Infection
When do Clotrimazole/Betamethasone possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Tingling or numbness
Rash
Swelling

Source: DailyMed

The following Clotrimazole/Betamethasone side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Blistering, burning, itching, peeling, dryness, redness, or other signs of skin irritation not present before use of this medicine

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

hives

Rare

Chills

cough

fever

hoarseness

lower back or side pain

painful or difficult urination

rash

stinging

swelling

Incidence not known

Blindness

blurred vision

change in vision

decreased vision

dry mouth

eye pain

full or round face, neck, or trunk

headache

irritability

nausea

reddish purple lines on the arms, face, legs, trunk, or groin

redness and scaling around the mouth

softening of the skin

stomach pain

tearing

unusual tiredness or weakness

vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Daisy Chau, PharmD
Reviewed by:
Daisy Chau, PharmD
Daisy Chau, PharmD, is the drug information pharmacist manager at GoodRx. She is licensed in California and has more than 6 years of experience working as a pharmacist in drug information.

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