What should I watch for?
Your condition will be monitored carefully while you are receiving this medicine.
Visit your doctor or health care professional for regular checks on your progress. You will need frequent blood checks. The side effects of the medicine can continue after you finish your treatment. Promptly report any side effects.
This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
Do not become pregnant while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Men should inform their doctors if they wish to father a child. Men and women need to use effective contraceptive methods during treatment and for at least 6 months after stopping this medicine. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
Black, tarry stools
blood in the urine
faintness, or lightheadedness when getting up suddenly from a lying or sitting position
painful or difficult urination
sores, ulcers, or white spots on the lips or in the mouth
tightness in the chest
troubled breathing, exertional
unusual bleeding or bruising
unusual tiredness or weakness
Bloating or swelling of the face, hands, lower legs, or feet
lower back or side pain
pounding, or irregular heartbeat or pulse
rapid weight gain
red or purple spots on the skin, varying in size and remaining after pushing the skin surface
Flushing of the face or neck
swelling of the eyelids, face, or lips
white patches on the tongue, in the mouth, or in the folds of the skin, including the genitals
Incidence not known
decreased urine output
dilated neck veins
extreme tiredness or weakness
feeling of discomfort
inability to move the arms and legs
inflammation of the joints
joint pain, stiffness, or swelling
muscle aches or pain
numbness, pain, tingling, or weakness
spitting up blood
sudden numbness and weakness in the arms and legs
swelling of the face, fingers, feet, or lower legs
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Fear or nervousness
burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings
lack or loss of strength
loss of appetite
painful cold sores or blisters on the lips, nose, eyes, or genitals
stomach discomfort, upset, or pain
swelling or inflammation of the mouth
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.