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Lemtrada

Lemtrada Side Effects

Robert Chad Hakim, PharmD, BCCCPKristianne Hannemann, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Kristianne Hannemann, PharmD
Last reviewed on November 27, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Less Common Side Effects

  • Itching
  • Thyroid problems
  • Fungal infection
  • Joint pain
  • Pain in arms and legs
  • Back pain
  • Diarrhea
  • Sinus inflammation
  • Mouth and throat pain
  • "Pins and needles" feeling
  • Dizziness
  • Stomach pain
  • Flushing
  • Vomiting

Lemtrada serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Autoimmune problems: see the risks and warnings section for more specific autoimmune problems and their associated signs and symptoms
  • Serious allergic and infusion reactions: low or high blood pressure, chest pain, low or high heart rate, headache, fever, rash, nausea, hives, difficulty sleeping, chills, flushing, fatigue, shortness of breath, dizziness
  • Stroke: sudden trouble speaking, droopy face, sudden confusion, numbness or weakness in the face, arm, or leg
  • Cancers: new lumps or swelling in your neck, pain in the front of the neck, changes in your voice, trouble swallowing or breathing, constant cough not due to an infection, changes in your skin
  • Inflammatory problems: see the risks and warnings section for more specific inflammatory problems and their associated signs and symptoms
  • Serious infections: fever, difficulty breathing, diarrhea, weakness, cough, stomach pain, sweating, chills, burning when you urinate, urinating more often

Source: DailyMed

The following Lemtrada side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Black, tarry stools

blood in the urine

chills

cough

diarrhea

dizziness, fainting, or lightheadedness when getting up suddenly from a lying or sitting position

fast heartbeat

fever

headache

itching, hives, skin rash

nausea

painful or difficult urination

pale skin

sore throat

sores, ulcers, or white spots on the lips or in the mouth

sweating

swollen glands

tightness in the chest

trouble breathing

unusual bleeding or bruising

unusual tiredness or weakness

vomiting

Less common

Bloating or swelling of the face, hands, lower legs, or feet

chest pain

hoarseness

lower back or side pain

muscle weakness

painful cold sores or blisters on the lips, nose, eyes, or genitals

pounding or irregular heartbeat or pulse

rapid weight gain

red or purple spots on the skin, varying in size and remaining after pushing the skin surface

tremor

unexplained nosebleeds

Rare

Bloody nose

flushing of the face or neck

swelling of the eyelids, face, or lips

white patches on the tongue, in the mouth, or in the folds of the skin, including the genitals

Incidence not known

Anxiety

back pain

blindness

blurred or double vision

chest pain or discomfort

confusion

dark urine

decreased urine output

decreased vision

difficulty in speaking

dilated neck veins

discouragement

double vision

drowsiness

extreme tiredness or weakness

eye pain

feeling of discomfort

feeling sad or empty

general feeling of tiredness and weakness

inability to move the arms, legs, or facial muscles

inability to speak

irregular breathing

irritability

joint pain, stiffness, or swelling

lack of appetite

light-colored stools

loss of interest or pleasure

muscle aches or pain

nightmares or unusually vivid dreams

numbness, pain, tingling, or weakness

pain or discomfort in the arms, jaw, back, or neck

painful or tender lymph glands in the neck, armpit, or groin

seizures

shakiness and unsteady walk

slow speech

spitting or coughing up blood

sudden numbness and weakness in the arms and legs

swelling of the face, fingers, feet, or lower legs

trouble concentrating

trouble sleeping

unsteadiness, trembling, or other problems with muscle control or coordination

upper right abdominal or stomach pain and fullness

yellow eyes and skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Fear or nervousness

Less common

Belching

bone pain

burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings

heartburn

indigestion

lack or loss of strength

stomach discomfort, upset, or pain

swelling or inflammation of the mouth

weight loss

Rare

Constipation

sensation of temperature change

sleepiness

stuffy nose

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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