Kynamro
Kynamro (mipomersen) is an injectable medication that helps lower cholesterol levels in people with a condition called homozygous familial hypercholesterolemia (HoFH). It's used together with other cholesterol-lowering medications and diet. This medication is no longer available in the United States.
What is Kynamro (mipomersen)?
Drug facts
Common questions about Kynamro (mipomersen)
Homozygous familial hypercholesterolemia (HoFH) is a type of rare genetic condition that causes lifelong high cholesterol. This condition raises "bad" cholesterol, like low-density lipoprotein cholesterol (LDL-C), in your blood. Too much "bad" cholesterol can cause atherosclerosis, where cholesterol builds up in your arteries (blood vessels) and blocks blood from flowing to important parts of your body. This can cause heart attacks, strokes, and other heart or blood circulation problems. So if HoFH is left untreated, this condition can lead to atherosclerosis earlier in life than usual and a higher risk of heart attack and stroke.
Kynamro (mipomersen) is a medication injected under the skin (subcutaneously) once a week to help lower a variety of "bad" cholesterol levels in your blood. These levels include low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (apo B), total cholesterol (TC), and non-high-density lipoprotein cholesterol (non-HDL-C). Kynamro (mipomersen) is given along with other cholesterol-lowering medications and proper diet to help lower "bad" cholesterol levels to lower your risk of atherosclerosis, heart attack, and stroke.
No, Kynamro (mipomersen) is no longer available in the United States.
It's unclear why Kynamro (mipomersen) was taken off the market, but the FDA withdrew its approval for this medication as of August 2019.
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Kynamro (mipomersen) dosage
Typical dosage for Kynamro (mipomersen)
Interactions between Kynamro (mipomersen) and other drugs
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.