Skip to main content
Fioricet With Codeine

Fioricet With Codeine Side Effects

Shifali Patel, PharmDMichelle Nguyen, PharmD
Reviewed by Shifali Patel, PharmD, Michelle Nguyen, PharmD
Last reviewed on January 13, 2022

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Drowsiness or sleepiness
  • Lightheadedness
  • Dizziness
  • Shortness of breath
  • Nausea
  • Vomiting
  • Stomach pain
  • Feeling intoxicated

Less Common Side Effects

  • Headache
  • Shaking
  • Tingling or numbness
  • Feeling agitated
  • Fainting
  • Tiredness or sluggishness
  • Heavy eyelids
  • High energy or excitement
  • Seizures
  • Depression
  • Confusion
  • Dry mouth
  • Excessive sweating
  • Difficulty swallowing
  • Heartburn
  • Gas
  • Constipation
  • Fast heart rate
  • Leg pain
  • Muscle pain or weakness
  • Frequent urination
  • Itching
  • Fever
  • Earache or ringing in ears
  • Stuffy nose

Fioricet With Codeine serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Respiratory depression (breathing problems): shortness of breath, wheezing, slowed breathing, tiredness or sleepiness during the day, anxiety, confusion
  • CNS depression (slowed brain function): sleepiness, dizziness, low heart rate, slowed breathing, muscle weakness, headache, slurred speech, blurred vision, confusion
  • Overdose: slowed breathing, small pupils, blue lips and fingertips, pale face, sweating, choking, unresponsiveness
  • Withdrawal in newborn babies: irritability, overactivity, abnormal sleeping pattern, excessive or high-pitched crying, body shaking (tremor), vomiting, diarrhea, unable to gain weight, breathing problems, fever, sweating, seizures
  • Withdrawal in adults: restlessness, watery eyes, runny nose, sleepiness, sweating, chills, muscle pain, back or joint pain, large pupils, irritability, anxiety, nervousness, weakness, stomach cramps, trouble falling asleep (insomnia), nausea, vomiting, diarrhea, high blood pressure, fast heart rate, seizures
  • Liver failure: yellow skin or eyes (jaundice), stomach pain or swelling, loss of appetite, nausea, vomiting, diarrhea, tiredness or weakness, confusion
  • Adrenal insufficiency (low cortisol levels): nausea, vomiting, stomach pain, anorexia, tiredness, weakness, dizziness, low blood pressure
  • Low blood pressure: dizziness, lightheadedness, feeling thirsty or dehydrated, not able to concentrate, tiredness or weakness, confusion, blurred vision, cold or pale skin, fast breathing
  • Intestinal blockage: stomach pain or cramps, stomach swelling, nausea, vomiting, diarrhea, constipation
  • Inflammation of the pancreas: stomach pain or tenderness, nausea, vomiting, diarrhea, fever, fast heart rate
  • Serious skin reactions: painful skin rash, blisters, skin itching or peeling, body aches, eye redness, cough, sore throat, fever
  • Serotonin syndrome: agitation, restlessness, anxiety, body shaking (tremors), shivering, stiff muscles, sweating, flushed skin, vomiting, diarrhea, high blood pressure, fast heart rate, fast breathing, large pupils
  • Serious allergic reaction: itchy, red rash (hives), shortness of breath, chest tightness, swelling of lips, tongue, face, or eyes
  • Seizures

Source: DailyMed

The following Fioricet With Codeine side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Confusion (mild)

mental depression

unusual excitement (mild)

Rare

Bleeding or crusting sores on the lips

chest pain or tightness

fever with or without chills

hive-like swellings on the eyelids, face, lips, or tongue

hives, itching, or skin rash

muscle cramps or pain

red, thickened, or scaly skin

seeing, hearing, or feeling things that are not there

seizures

sore throat

sores, ulcers, or white spots in the mouth

swollen or painful glands

trouble breathing

Incidence not known

Agitation

cough

darkening of the skin

diarrhea

difficulty with swallowing

dizziness

fainting

fever

loss of appetite

nausea

overactive reflexes

poor coordination

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

restlessness

shivering

talking or acting with excitement you cannot control

trembling or shaking

twitching

unusual tiredness or weakness

vomiting

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Anxiety (severe)

cold and clammy skin

confusion (severe)

dizziness, lightheadedness, drowsiness, or weakness (severe)

excitement (severe)

increased sleepiness in babies (more than usual)

increased sweating

irritability (severe)

limpness (in babies)

nausea

restlessness (severe)

slow, fast, or irregular heartbeat

slurred speech

stomach cramps or pain

swelling, pain, or tenderness in the upper abdomen or stomach area

trembling or shaking of the hands or feet

trouble sleeping (severe)

unusually slow breathing

vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Bloated or "gassy" feeling

drowsiness (mild)

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

why trust our exports reliability shield

Why trust our experts?

Shifali Patel, PharmD, worked as a pharmacist in a hospital setting for 3 years prior to joining GoodRx. As a hospital pharmacist, she reviewed medication orders for safety and accuracy, optimized medication therapy, provided clinical information to healthcare providers, and educated people about their medications.
Michelle Nguyen, PharmD, has been a clinical pharmacist for 6 years (and counting). She has a diverse skill set within managed care pharmacy, specifically in the settings of a medical group, pharmacy benefit manager (PBM), and health plan.

Was this page helpful?