
Egaten
Egaten (triclabendazole) is a medication used to treat fascioliasis, an infection caused by liver flukes, a type of parasitic worm. It's FDA-approved for use in children and adults 6 years and older. Egaten (triclabendazole) comes in 250 mg tablets and is a short treatment made up of two doses taken by mouth, 12 hours apart. Common side effects include stomach pain and nausea. It has many potential interactions with other medications so it's best to review a current list of your medications with your care team.
What is Egaten (triclabendazole)?
What is Egaten (triclabendazole) used for?
- Fascioliasis in people 6 years of age or older
How Egaten (triclabendazole) works
Egaten (triclabendazole) is an anthelminthic. The way it works to treat fascioliasis isn't fully understood. But it's believed the medication kills the worms by disrupting vital processes for their survival, such as movement and reproduction.
Drug facts
| Common Brands | Egaten |
|---|---|
| Drug Class | Anthelmintic |
| Controlled Substance Classification | Not a controlled medication |
| Generic Status | No lower-cost generic available |
| Availability | Prescription only |
Side effects of Egaten (triclabendazole)
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Stomach pain (93%)
- Excessive sweating (25%)
- Nausea (18%)
- Reduced appetite (18%)
- Headache (14%)
- Hives (11%)
- Vomiting (7%)
- Diarrhea (7%)
Less Common Side Effects
- Shortness of breath
- Weakness
- Chest pain or discomfort
- Cough
- Fever
- Yellowing of skin or whites of the eyes
- Feeling like you're spinning (vertigo)
- Itching
Egaten (triclabendazole) serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Heart rhythm problems (QT prolongation): abnormal heart rhythm, chest pain, shortness of breath, fainting, lightheadedness
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Pros and cons of Egaten (triclabendazole)
Pros
- Treatment of choice for fascioliasis
- Only need to take two doses
- Tablets can be cut in half or crushed and mixed with applesauce
- FDA approved for people 6 years and older
Cons
- Commonly causes stomach pain and nausea
- Only stable for 4 hours if it's mixed with applesauce
- Must be taken with food
- No lower-cost generic available
Pharmacist tips for Egaten (triclabendazole)
- Take Egaten (triclabendazole) with food. Food raises the amount of medication that gets absorbed into your body and helps the medication stay in your body longer in order to fight the infection.
- Make sure to take both doses of Egaten (triclabendazole) as prescribed. Taking only one dose can cause your infection to not be treated properly.
- Egaten (triclabendazole) can cause an abnormal heart rhythm, which can be dangerous. Let your prescriber know if you experience a fluttering sensation in your chest or feel faint.
- Tell your prescriber if you're pregnant, planning to become pregnant, or breastfeeding before taking Egaten (triclabendazole), because it's not known if this medication can harm your unborn or breastfed baby.
Risks and warnings for Egaten (triclabendazole)
Egaten (triclabendazole) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Heart rhythm problems (QT prolongation)
- Risk factors: History of QT prolongation | Taking medications that can cause QT prolongation | Liver problems | Electrolyte imbalance
Egaten (triclabendazole) can raise the risk of a heart rhythm condition called QT prolongation, or long QT syndrome. This is when your heart doesn't contract and relax when it's supposed to, which leads to an abnormal heart rhythm. Your prescriber will order an echocardiogram (ECG) test to check your heart's electrical signals if you have certain health conditions that put you at risk for an abnormal heart rhythm. Call your prescriber right away if you have symptoms such as chest pain, fainting, fluttering in your chest, or a racing heart.
Egaten (triclabendazole) dosage
| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 4 tablets of 250mg | 1 package | $4.41 | $4.41 |
Typical dosage for Egaten (triclabendazole)
The typical dose is 10 mg/kg of body weight by mouth taken 12 hours apart for two doses.
How much does Egaten (triclabendazole) cost?
$4.41
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