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dobutamine

Generic
Used for Heart Failure
Used for Heart Failure

Dobutamine is an injectable medication used in the hospital for people who have sudden, severe worsening of heart failure. It helps your heart pump, which improves blood flow throughout the body. This medication is only meant for short-term use.

Last reviewed on January 30, 2023
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What is Dobutamine?

What is Dobutamine used for?

  • Short-term treatment of sudden, severe worsening of heart failure

How Dobutamine works

Drug Facts

Common BrandsNo brand available
Drug ClassBeta agonist
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
faqs

Frequently asked questions about Dobutamine

What is dobutamine used for?
Dobutamine is used in the hospital to manage sudden, severe worsening of heart failure. Heart failure happens when your heart isn't strong enough to keep pumping blood throughout your body. Over time, blood and fluid start to build up in your body, especially in the lungs and legs. This can cause shortness of breath and swelling. The sudden, severe worsening of heart failure can be a life-threatening situation. If this happens, you need immediate medical attention, and you'll typically need to be hospitalized for care.
How does dobutamine work?
Dobutamine is a beta agonist. It acts on signaling proteins called beta-adrenergic receptors in the heart and blood vessels. When dobutamine attaches to these receptors, it lets your heart squeeze more and raises your heart rate. This keeps your blood pressure from dropping too low.
How is dobutamine given?
Dobutamine is given as an injection through the veins (intravenously or IV) by a healthcare provider in the hospital. This injection runs continuously, usually for no more than several hours. But your provider will determine how long you need dobutamine to keep your condition stable.
How much dobutamine will I receive?
The dose of dobutamine varies from one person to another because it's based on your body weight and response to the medication. Some things that your care team looks at to see how you're responding to the medication include your blood pressure, heart rate, and other indicators of heart function. Hospitals typically have a specific program in place with steps that outline how to monitor and change the dose of dobutamine. This makes sure the medication works well and is as safe as possible for you.
What are the side effects of dobutamine?
Dobutamine is typically a well-tolerated medication and doesn't have a lot of side effects. Some possible side effects include changes in blood pressure (usually higher and rarely lower), irregular heart rate, and injection-site reactions (e.g., skin inflammation). Dobutamine contains a sulfite, which might cause serious and possibly life-threatening allergic reactions in some people.
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alternatives

What are alternatives to Dobutamine?

There are a number of medications that your doctor can prescribe in place of Dobutamine. Compare a few possible alternatives below.
Dobutamine
Used for:
  • Short-term treatment of sudden, severe worsening of heart failure

Used for:
  • Short-term treatment of sudden, severe worsening of heart failure

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References

Best studies we found

Ashkar, H., et al. (2023). Dobutamine. StatPearls.

Hainan Poly Pharm. Co., Ltd. (2023). DOBUTAMINE injection, solution, concentrate [package insert]. DailyMed.

Teerlink, J. R., et al. (2015). Acute decompensated heart failure update. Current Cardiology Reviews.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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