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Metabolic Dysfunction-Associated Steatotic Liver Disease

Risk Factors for MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease): Diabetes, High Blood Pressure, and More

These are some of the conditions that can lead to big problems in your liver.

Marisa Taylor KarasPatricia Pinto-Garcia, MD, MPH
Written by Marisa Taylor Karas | Reviewed by Patricia Pinto-Garcia, MD, MPH
Updated on October 13, 2025
Featuring Alyson Fox, MD, MSCEReviewed by Patricia Pinto-Garcia, MD, MPH | October 9, 2025

When fat builds up in your liver, you may have a type of liver condition known as metabolic dysfunction-associated steatotic liver disease, or MASLD. MASLD refers to fat buildup in the liver and it’s often linked to metabolic syndrome.

In this video, learn which conditions increase the risk of MASLD, formerly known as non-alcoholic fatty liver disease, according to Alyson Fox, MD, MSCE, Transplant Hepatologist at Columbia University’s Irving Medical Center. 

References

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Marisa Taylor Karas is a freelance journalist based in Brooklyn who has covered health, gender, and technology for 15 years. She previously worked at The Wall Street Journal, The Guardian, and Al Jazeera America, among other publications, and also served as managing editor of the Mellon Foundation in New York City.
Patricia Pinto-Garcia, MD, MPH, is a medical editor at GoodRx. She is a licensed, board-certified pediatrician with more than a decade of experience in academic medicine.

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