Medications for connective-tissue disorders are used to treat various conditions, such as fibrodysplasia ossificans progressiva and dsmoid tumors. They work by breaking down excess collagen or preventing abnormal bone growth. Common classes include collagenase enzymes and retinoic acid receptor agonists. Xiaflex (collagenase clostridium histolyticum) is an injectable treatment that helps break down collagen buildup in tissues. Sohonos (palovarotene) is an oral medication that prevents abnormal bone formation.