Compare Vagifem vs. Estring
Head-to-head comparisons of medication uses, side effects, warnings, and more.
- VagifemEstring (estradiol)
- VagifemEstring (estradiol)
Summary of Vagifem vs. Estring
Summary for Estrogen replacementPrescription onlyVagifem (estradiol vaginal insert) is used to treat vaginal dryness, irritation, and burning caused by menopause. It contains estradiol, a type of estrogen that helps to raise your hormone levels to ease these symptoms. You'll usually use one insert with an applicator twice a week (after using it daily for the first 2 weeks). Common side effects include back pain, diarrhea, and vaginal yeast infection.
Summary for Estrogen replacementPrescription onlyEstring (estradiol) is an estrogen vaginal ring used as part of hormone replacement therapy (HRT) to treat moderate-to-severe menopause symptoms in and around the vagina, such as vaginal dryness, burning, and irritation. The ring is inserted into the vagina and stays in place for 3 months, releasing a steady dose of estrogen directly where it's needed. Common side effects include headache, vaginal discharge, and vaginal yeast infections.
Indications of Vagifem vs. Estring
Indications for•Vaginal dryness, burning, and irritation due to menopauseIndications for•Vaginal dryness, burning, and irritation due to menopausePros and Cons of Vagifem vs. Estring
Pros and Const for Estrogen replacementPros•After the first 2 weeks, only need to use twice a week•Works directly at the site of application to relieve vaginal symptoms•Comes preloaded in an easy-to-use applicatorCons•Can cause vaginal yeast infections•Doesn't treat other menopause symptoms like hot flashes or night sweatsPros and Const for Estrogen replacementPros•Can be inserted by you or a healthcare professional•Only needs to be changed every 3 months•Works directly at the site of application to relieve vaginal symptomsCons•Can cause vaginal yeast infections•Doesn't treat other menopause symptoms like hot flashes or night sweatsCommon Side Effects of Vagifem vs. Estring
Common Side Effects for•Vaginal yeast infections (8%)•Vaginal itching (8%)•Back pain (7%)•Diarrhea (5%)Common Side Effects for•Headache (13%)•Vaginal discharge (7%)•Vaginal yeast infection (6%)•Back pain (6%)•Vaginal inflammation (5%)•Vaginal discomfort or pain (5%)•Upper respiratory infection (5%)•Vaginal bleeding (4%)•Bacterial growth in the vagina (4%)•Arthritis (4%)•Trouble sleeping (4%)•Stomach pain (4%)•Sinus inflammation (4%)•Nausea (3%)•Flu-like symptoms (3%)•Joint pain (3%)Warnings of Vagifem vs. Estring
Common Side Effects for•Risk for blood clots and related complications•Risk for uterine cancer (also called endometrial cancer)•Risk for breast cancer•Risk for ovarian cancer•Risk for dementia•Gallbladder or liver problems in certain people•High triglyceride (fat) levels•Changes in calcium levels in certain people•Low thyroid hormone levels•Buildup of fluids in your body (fluid retention)•Worsening of certain other health conditions•Vaginal irritation with applicator useCommon Side Effects for•Risk for blood clots and related complications•Risk for uterine cancer (also called endometrial cancer)•Risk for breast cancer•Risk for ovarian cancer•Risk for dementia•Gallbladder or liver problems in certain people•High triglyceride (fat) levels•Changes in calcium levels in certain people•Low thyroid hormone levels•Buildup of fluids in your body (fluid retention)•Worsening of certain other health conditions•Vaginal irritation and infectionsPrices with our coupons for Vagifem vs. Estring
Browse medications
View AllResearch prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.