Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Sublocade vs. Brixadi

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Sublocade (buprenorphine)
    Brixadi (buprenorphine)
  • Sublocade (buprenorphine)
    Brixadi (buprenorphine)

  • Summary of Sublocade vs. Brixadi

    Summary for Opioid partial agonist
    Prescription only

    Sublocade (buprenorphine) is an injection that's given under the skin by a healthcare provider for moderate-to-severe opioid use disorder. Treatment is given along with counseling and social and emotional support. This medication is convenient because you only need a dosage once a month. But it's only for people who've previously used another form of buprenorphine (e.g., Suboxone, buprenorphine (Subutex)). Side effects of Sublocade (buprenorphine) include headache, constipation, and injection-site reactions (e.g., pain, swelling). This medication is brand name only.

    Summary for Opioid partial agonist
    Prescription only

    Brixadi (buprenorphine) is an injection given under the skin by a healthcare professional for moderate to severe opioid use disorder. It's typically given along with counseling, as well as social and emotional support. Brixadi (buprenorphine) is conveniently given once per week or once per month, but it's only for people who've previously tolerated another form of buprenorphine (e.g., buprenorphine (Zubsolv) film or buprenorphine (Subutex)). Some side effects of Brixadi (buprenorphine) include injection site reactions (e.g., pain or swelling), headache, and constipation.

  • Indications of Sublocade vs. Brixadi

    Indications for
    •Moderate-to-severe opioid use disorder in adults who've already started treatment with a buprenorphine-containing medication
    Indications for
    •Moderate to severe opioid use disorder in adults who've already started treatment with a buprenorphine-containing medication.

  • Pros and Cons of Sublocade vs. Brixadi

    Pros and Const for Opioid partial agonist
    Pros
    •Works well to treat moderate-to-severe opioid use disorder
    •Given just once per month
    •Injections are given only by trained healthcare providers registered with the Sublocade REMS program to make sure it's as safe for you as possible
    Cons
    •Given as an injection under the skin
    •Need to go to the provider's office or clinic regularly to get injections
    •Has serious risks like slow breathing
    Pros and Const for Opioid partial agonist
    Pros
    •Works well to treat moderate to severe opioid use disorder
    •Given once per week or once per month
    •Only trained healthcare providers who are registered with the REMS program can give you Brixadi (buprenorphine), to make sure this medication is as safe for you as possible
    Cons
    •Injection only
    •Needs to go to the provider's office regularly to receive injection
    •Has a lot of potential risks and side effects, such as breathing problems and sleepiness

  • Common Side Effects of Sublocade vs. Brixadi

    Common Side Effects for
    •Injection-site reactions (pain, itching, redness, bruising, swelling; 14-19%)
    •Headache (9%)
    •Constipation (8-9%)
    •Nausea (8-9%)
    •Vomiting (6-9%)
    Common Side Effects for
    •Injection site reactions, including pain, itching, and swelling (up to 21%)
    •Headache (8%)
    •Constipation (8%)
    •Nausea (7%)
    •Difficulty sleeping (6%)
    •Urinary tract infection (5%)

  • Warnings of Sublocade vs. Brixadi

    Common Side Effects for
    •Not for intravenous (IV) administration
    •Risk for addiction and misuse
    •Dangerously slow breathing (respiratory depression)
    •Harm to newborns
    •Low adrenal hormone levels
    •Risk of withdrawal symptoms
    •Liver damage
    •Risks with treatment for pain
    •Not for use in people who haven't taken opioids before
    •Life-threatening heart rhythm problems (QT prolongation)
    Common Side Effects for
    •Not for intravenous (IV) administration
    •Risk for addiction, misuse, and abuse
    •Dangerously slow breathing (respiratory depression)
    •Harm to newborns
    •Low adrenal hormone levels
    •Risk of withdrawal symptoms
    •Liver damage
    •Risks with treatment for pain
    •Not for use in people who haven't taken opioids before
    •Life-threatening heart rhythm problems (QT prolongation)

  • Prices with our coupons for Sublocade vs. Brixadi

    Learn more about Sublocade
    Learn more about Brixadi

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.