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Compare Segluromet vs. Synjardy

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Segluromet (ertugliflozin / metformin)
    Synjardy
  • Segluromet (ertugliflozin / metformin)
    Synjardy

  • Summary of Segluromet vs. Synjardy

    Summary for SGLT2 inhibitor / Biguanide
    Prescription only

    Segluromet is a medication that combines two ingredients: ertugliflozin (a sodium glucose cotransporter 2 inhibitor) and metformin (a biguanide). It helps lower blood sugar levels in adults with Type 2 diabetes. Segluromet works best when you also follow a diabetes-friendly diet and exercise regularly. This medication comes as a tablet that's taken by mouth twice a day with food. Side effects can include diarrhea, stomach upset, and genital yeast infections. Segluromet is only available as a brand-name medication.

    Summary for SGLT2 inhibitor / Biguanide
    Prescription only

    Synjardy is a tablet containing empagliflozin (an SGLT2 inhibitor) and metformin (a biguanide). It helps lower blood sugar in people with Type 2 diabetes when used with a balanced diet and regular exercise. Synjardy can also help lower the risk of serious problems in adults with Type 2 diabetes who have heart disease, heart failure, or chronic kidney disease (CKD). Immediate-release tablets (IR) are for people 10 years and older and are taken twice a day. The extended-release tablets (XR) are only for adults and are taken once a day. Side effects include urinary tract infections and genital yeast infections.

  • Indications of Segluromet vs. Synjardy

    Indications for
    •Type 2 diabetes
    Indications for
    •Type 2 diabetes
    •Lowering the risk of death due to heart problems in adults with Type 2 diabetes and heart disease
    •Lowering the risk of hospitalization and death due to heart problems in adults with Type 2 diabetes and heart failure
    •Lowering the risk of worsening kidney problems, hospitalization, and death due to heart problems in adults with Type 2 diabetes and chronic kidney disease (CKD)

  • Pros and Cons of Segluromet vs. Synjardy

    Pros and Const for SGLT2 inhibitor / Biguanide
    Pros
    •Two diabetes medications combined into one tablet so there's less pills to take each day
    •Adjustable dose based on blood sugar levels
    Cons
    •Might make you urinate more
    •Not for people with Type 1 diabetes
    •Not recommended during pregnancy or while breastfeeding
    Pros and Const for SGLT2 inhibitor / Biguanide
    Pros
    •Combines two medications into one tablet for convenience
    •Not likely to cause weight gain
    •Available in both immediate-release and extended-release versions
    •Immediate-release tablets are okay for children 10 years and older to take
    Cons
    •Need to take with food
    •Might cause urinary tract infections or genital yeast infections
    •Not safe for people with severe kidney problems or on dialysis
    •Not approved for people with Type 1 diabetes

  • Common Side Effects of Segluromet vs. Synjardy

    Common Side Effects for

    Side effects from ertugliflozin:

    •Genital fungal infection
    •Urinary tract infection
    •Headache

    Side effects from metformin:

    •Diarrhea
    •Nausea
    •Vomiting
    •Passing gas
    •Stomach discomfort
    •Indigestion
    •Weakness
    •Headache
    Common Side Effects for
    •Low blood sugar (up to 16%)
    •Urinary tract infection (up to 9%)
    •Upper respiratory tract infection or common cold (up to 8%)

    Note: Side effect percentages were reported by adults taking empagliflozin, metformin, and a sulfonylurea.

  • Warnings of Segluromet vs. Synjardy

    Common Side Effects for
    •Lactic acidosis
    •Serious genital infections and urinary tract infections
    •Low fluids in the body (leading to low blood pressure, dehydration, or kidney problems)
    •Ketoacidosis
    •Leg and foot amputations
    •Low blood sugar (hypoglycemia) when taken with certain diabetes medications
    •Low vitamin B12 levels
    Common Side Effects for
    •Lactic acidosis
    •Ketoacidosis
    •Low fluids in the body (leading to low blood pressure, dehydration, or kidney problems)
    •Genital infections and urinary tract infections
    •Low blood sugar (hypoglycemia) when taken with certain diabetes medications
    •Leg and foot amputations
    •Serious allergic reaction
    •Low vitamin B12 levels

  • Prices with our coupons for Segluromet vs. Synjardy

    Learn more about Segluromet
    Learn more about Synjardy

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