Pavblu
(aflibercept)
Get free couponsEylea
(aflibercept)
Get free couponsSummary for Pavblu
Pavblu (aflibercept or aflibercept-ayyh) is a biosimilar to Eylea. It's a VEGF inhibitor that treats eye conditions related to the retina that can cause vision loss. It’s FDA approved for adults with wet age‑related macular degeneration (AMD) as well as macular edema after retinal vein occlusion (RVO). It's also for diabetic macular edema (DME) and diabetic retinopathy (DR). Pavblu (aflibercept) is injected into the eye by a trained eye specialist at regular intervals. Side effects include bleeding on the surface of the eye, eye pain, and higher eye pressure.
Indications for Pavblu
- Wet age‑related macular degeneration (wet AMD)
- Macular edema following retinal vein occlusion (MEfRVO)
- Diabetic macular edema (DME)
- Diabetic retinopathy (DR)
Pros and Cons for Pavblu
Pros
- FDA approved for 4 major retinal conditions
- Less frequent dosing after the first few injections for many people
- Given by an eye specialist in clinic, so you don’t self‑inject
Cons
- Need ongoing eye injections and clinic visits
- Can raise your eye pressure or cause bleeding on the surface of your eye
- Small risk of serious eye infection, retinal problems, and blood clots
Common Side Effects for Pavblu
Wet AMD:
- Blood spot on the whites of eye (25%–27%)
- Cataract (7%–13%)
- Eye pain (9%–10%)
- Floaters (6%–8%)
- Vitreous detachment (6%–8%)
- Higher eye pressure (5%–7%)
Macular edema after RVO:
- Eye pain (13%)
- Blood spot on the whites of eye (12%)
- Higher eye pressure (8%)
- Floaters (5%)
- Corneal surface defect (5%)
Diabetic macular edema (DME):
- Blood spot on the whites of eye (28%–31%)
- Cataract (8%-19%)
- Eye pain (9%–11%)
- Higher eye pressure (5%–9%)
- Floaters (6%-8%)
- Vitreous detachment (3%–8%)
- Corneal surface defect (5%–7%)
Warnings for Pavblu
- Eye infection, retinal detachment, and other eye damage
- Higher eye pressure
- Potential risk of blood clots
Summary for Eylea
Eylea (aflibercept) is used for certain eye conditions related to the retina (a layer of cells in the back of the eye) for both adults and premature babies. It's typically injected into the eye by an eye specialist. Eylea (aflibercept) is only available at specialty pharmacies or distributors, so a provider will help you set that up.
Indications for Eylea
Pros and Cons for Eylea
Pros
- Can help with multiple eye conditions related to the retina
- Typically needs to be injected once every 1 to 2 months for adults, so it's convenient for people with a busy schedule
- Offers another treatment option for babies with ROP aside from laser treatment
Cons
- Not a safe option for people with history of blood clots (e.g., stroke, heart attack)
- Injection into the eye can lead to greater risk of eye infection or injury
- Might not be a safe option for people with uncontrolled high eye pressure (e.g., glaucoma)
Common Side Effects for Eylea
Adults
- Blood spots on the whites of eye (12-31%)
- Cataract (Up to 19%)
- Eye pain (9-13%)
- Raised eye pressure (2-9%)
- Greater amount of eye floaters (1-8%)
Children
- Blood spots on the whites of the eye (5-9%)
- Retinal detachment (5-6%)
- Raised eye pressure (0-4%)
Warnings for Eylea
- Eye infection and damage
- Higher eye pressure
- Heart attack or stroke
Prices with our coupons for Pavblu vs. Eylea
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