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Ditropan XL vs. Tolterodine

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Oxybutynin

 

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Tolterodine

(Detrol)

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Summary for Ditropan XL

Prescription only

Oxybutynin is used to treat overactive bladder (OAB). Oral oxybutynin is available as a short-acting tablet and solution that is taken 2 to 4 times a day. It also comes as a long-acting tablet that's taken once daily (brand name Ditropan XL). Some common side effects of oxybutynin include dry mouth, constipation, and dizziness. Older adults typically lower doses of this medication to lower the risk for side effects.

Indications for Ditropan XL

  • Overactive bladder
  • Incontinence in children due to a neurologic (brain) condition, such as spina bifida

Pros and Cons for Ditropan XL

Pros

  • Works well to improve symptoms of OAB
  • Available as a convenient, once-daily tablet (Ditropan XL)
  • Can be used in children as young as 5 years old
  • Available as an oral liquid, good for people who have trouble swallowing tablets

Cons

  • Commonly causes dry mouth as a side effect
  • Higher risk of side effects in people age 65 and older
  • Can cause dizziness and drowsiness
  • Shouldn't be used by people who have untreated narrow-angle glaucoma, difficulty urinating, or movement problems with the stomach or intestines

Common Side Effects for Ditropan XL

  • Dry mouth (up to 71%)
  • Dizziness (up to 17%)
  • Constipation (up to 15%)
  • Sleepiness (up to 14%)
  • Nausea (up to 12%)
  • Blurry vision (up to 10%)

Warnings for Ditropan XL

  • Swelling of face, lips, tongue (angioedema)
  • Hallucinations, drowsiness, and confusion
  • Worsening of other conditions
  • Heat exhaustion

Summary for Tolterodine

Prescription only

Tolterodine (Detrol) is used to treat overactive bladder (OAB) in adults. It's an anticholinergic medication that helps with bladder control to lessen the need to go to the restroom suddenly or often. The immediate-release tablet (Detrol) is taken by mouth twice a day. There's also an extended-release capsule (Detrol LA) that's taken just once a day. Both formulations come in brand-name and generic-name versions. Tolterodine (Detrol) can commonly cause dry mouth. Other side effects can include headache and constipation.

Indications for Tolterodine

Pros and Cons for Tolterodine

Pros

  • Works well to help lessen your urge to urinate
  • Might cause less dry mouth than oxybutynin
  • Also available in an extended-release version that's taken only once a day

Cons

  • Can cause uncomfortable dry mouth and constipation
  • Can make you feel sleepy or dizzy, which can raise your risk of falls
  • Can't take if you have an allergy to another OAB medication called Toviaz (fesoterodine)

Common Side Effects for Tolterodine

Immediate-release tablets:

  • Dry mouth (35%)
  • Headache (7%)
  • Constipation (7%)
  • Stomach pain (5%)
  • Dizziness or feeling like you're spinning (5%)

Extended-release capsules:

  • Dry mouth (23%)
  • Headache (6%)
  • Constipation (6%)
  • Stomach pain (4%)

Warnings for Tolterodine

  • Serious allergic reaction and swelling (angioedema)
  • Dizziness and drowsiness
  • Caution use in people with narrow-angle glaucoma
  • Caution use in people with trouble urinating
  • Caution use in people with problems causing gut blockage
  • Caution use in people with myasthenia gravis
  • Caution use in people with certain heart rhythm problems

Prices with our coupons for Ditropan XL vs. Tolterodine

Price Card Drug Icon
Oxybutynin ER30 tablets / 10mg
$8.50$67.30
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Price Card Drug Icon
Tolterodine60 tablets / 2mg
$25.57$203.81
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