Head-to-head comparisons of medication uses, side effects, warnings, and more.
Kisunla (donanemab)
Leqembi (lecanemab)
Kisunla (donanemab)
Leqembi (lecanemab)
Summary of Kisunla vs. Leqembi
Summary for Amyloid beta-directed antibody
Prescription only
Kisunla (donanemab or donanemab-azbt) is FDA approved to treat people with early Alzheimer's disease (AD). It's a type of monoclonal antibody called an amyloid beta-directed antibody. Kisunla (donanemab) is given as an infusion into a vein by a healthcare professional every 4 weeks. Potential side effects include small bleeds on the brain and headache.
Summary for Amyloid beta-directed antibody
Prescription only
Leqembi (lecanemab or lecanemab-irmb) is FDA approved to treat people with early Alzheimer's disease. This is when they have mild cognitive impairment or mild dementia. Leqembi (lecanemab) is a type of monoclonal antibody that's given as an infusion into a vein. It's given at an infusion center once every 2 weeks. Later on during treatment, there's an option to get the infusions once every 4 weeks. Common side effects include infusion-related reactions and headache. Leqembi (lecanemab) is not a cure for Alzheimer's disease.