Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Panobinostat (Farydak) and cyclophosphamide (Cytoxan) are both medications that can be used to treat multiple myeloma, a type of bone marrow cancer. However, they belong to different medication classes and have important differences. Panobinostat is a histone deacetylase inhibitor that works by preventing cancer cells from multiplying, but it has been discontinued in the United States. Cyclophosphamide, on the other hand, is an alkylating agent that damages the DNA of cancer cells, leading to their death. It is still available and used for various cancers and nephrotic syndrome in children. Cyclophosphamide can be taken orally or intravenously, while panobinostat was only available in oral form. Cyclophosphamide requires careful monitoring due to potential side effects like bladder damage and low blood cell count.
Farydak (panobinostat)
Cyclophosphamide
Farydak (panobinostat)
Cyclophosphamide
Summary of Farydak vs. Cyclophosphamide
Summary for Histone deacetylase inhibitor
Farydak (panobinostat) is a medication that's taken by mouth for the treatment of multiple myeloma (a type of bone marrow cancer). It was initially approved to be a part of a treatment that also included Velcade (bortezomib) and dexamethasone (Taperdex). It was only to be used by certain people for whom previous chemotherapy treatments didn't work well. Farydak (panobinostat) has been discontinued by the manufacturer and is no longer available in the United States.
Summary for Anticancer agent
Prescription only
Cyclophosphamide is an anticancer medication used in the treatment of many types of adult and childhood cancers, as well as a certain type of kidney problem in children (nephrotic syndrome). It’s typically used in combination with other anticancer medications. Depending on the treatment regimen, cyclophosphamide can be taken as a pill by mouth or injected into the veins (intravenously or IV). This medication can cause serious bladder and kidney problems, so it’s important to stay well hydrated during treatment.