Cerdelga
(eliglustat)
Get free couponsCerezyme
(imiglucerase)
Get free couponsSummary for Eliglustat
Cerdelga (eliglustat) is a medication that belongs to a drug class known as glucosylceramide synthase inhibitors. This medication is FDA-approved as long-term treatment for certain adults with a rare genetic condition called Gaucher disease type 1 (GD1). Cerdelga (eliglustat) is a capsule that's taken by mouth. Side effects can include fatigue, headache, and nausea.
Indications for Eliglustat
- Gaucher disease type 1 (GD1) in certain adults
Pros and Cons for Eliglustat
Pros
- First-choice treatment option in most adults with GD1
- Can take with or without food
- Taken by mouth, so it doesn’t require an IV or port like enzyme replacement therapy (ERT)
- More convenient than ERT since you don't need frequent trips to the infusion center
Cons
- Requires genetic testing before you start treatment
- Has many drug interactions (such as with certain antidepressants, antibiotics, and anti-seizure medications)
- Might not be able to use if you have certain liver, kidney, or heart problems because of the risk for serious side effects
- Not for use in children because it hasn’t been studied
Common Side Effects for Eliglustat
- Fatigue (14%)
- Headache (13%)
- Nausea (12%)
- Diarrhea (12%)
- Back pain (12%)
- Pain in arm or leg (11%)
- Upper stomach pain (10%)
Warnings for Eliglustat
- Heart rhythm problems
Summary for Imiglucerase
Cerezyme (imiglucerase) is a form of enzyme replacement therapy (ERT) used to treat Type 1 Gaucher disease in adults and children 2 years of age or older. It's given as an intravenous (IV) infusion by a healthcare provider. Overall, Cerezyme (imiglucerase) is well tolerated, but it can cause allergic or infusion-related reactions like hives or difficulty breathing.
Indications for Imiglucerase
- Type 1 Gaucher disease in adults and children 2 years of age or older
Pros and Cons for Imiglucerase
Pros
- Can be used long-term, for at least 20 years, to treat Type 1 Gaucher disease
- Can be used in children as young as 2 years of age
- Safe to use if pregnant or breastfeeding
- Fewer side effects compared to oral medications for Gaucher disease type 1
Cons
- Might require frequent trips to the infusion center to receive treatment
- Takes 1 to 2 hours to receive each infusion
- Potential for allergic or infusion reactions with long-term use
- Requires IV access, so it's not as convenient as taking a pill
Common Side Effects for Imiglucerase
- Itching
- Fever
- Rash
- Chills
- Chest discomfort
Warnings for Imiglucerase
- Allergic or infusion-related reactions
Prices with our coupons for Eliglustat vs. Imiglucerase
Browse medications by letter
Show AllBrowse prescription and over-the-counter medications from A to Z, compare drug prices, and start saving.
