Blujepa vs. Macrobid for Urinary Tract Infection: Important Differences and Potential Risks.

Blujepa

(gepotidacin)

Nitrofurantoin

(Macrobid)

Summary for Blujepa

Prescription only

Blujepa (gepotidacin) is an antibiotic pill used to treat certain common infections, including uncomplicated urinary tract infections (UTIs) and gonorrhea in some people 12 years and older. It's the first antibiotic in a new class that works differently from others. The dose is taken twice a day for 5 days for a UTI, or as two high doses 12 hours apart for gonorrhea. Common side effects include diarrhea, nausea, and stomach pain.

Indications for Blujepa

Uncomplicated urinary tract infections (UTIs) in women and girls 12 years and older who weigh at least 40 kg (88 lbs)
Uncomplicated urinary and genital gonorrhea in people 12 years and older who weigh at least 45 kg (99 lbs) when other treatment options aren't available

Pros and Cons for Blujepa

Pros

Only need to take it for a short amount of time
Might work better for some people when other treatments haven’t helped
Approved for adults and children as young as 12 years old

Cons

Commonly causes diarrhea, nausea, and stomach pain
Interacts with many medications
Not recommended for people with serious kidney or liver problems

Common Side Effects for Blujepa

UTI:

Diarrhea (16%)
Nausea (9%)
Stomach pain (4%)
Passing gas (3%)
Headache (2%)
Soft stool (2%)
Dizziness (2%)
Vomiting (2%)
Vaginal yeast infection (1%)

Gonorrhea:

Diarrhea (49%)
Nausea (24%)
Stomach pain (8%)
Vomiting (6%)
Passing gas (6%)
Dizziness (5%)
Soft stool (5%)
Headache (3%)
Tiredness (3%)
Sweating (2%)

Warnings for Blujepa

Heart rhythm problems (QT prolongation)
Build-up of acetylcholine
Severe allergic reactions
Diarrhea from Clostridioides difficile infection

Summary for Macrobid

Prescription only

Nitrofurantoin (Macrobid) is an antibiotic used to treat or prevent a urinary tract infection (UTI). Some side effects include nausea, headache, and gas. It can also make your urine turn dark yellow or brown. Nitrofurantoin (Macrobid) doesn't have many interactions with other medications. There's a lower-cost generic version of nitrofurantoin (Macrobid) available.

Indications for Macrobid

Treatment or prevention of urinary tract infections

Pros and Cons for Macrobid

Pros

Works well to treat and prevent UTIs
Available as both a capsule and a flavored oral suspension
Safe to take if you're allergic to other antibiotics like penicillin or sulfa medications (e.g., Bactrim, Septra (sulfamethoxazole / trimethoprim))

Cons

Might need to take up to four times a day (depending on the formulation)
Can interact with certain types of antacids, travel vaccines, and lab tests
Can harm your lungs, liver, and nerves if taken for a long period of time

Common Side Effects for Macrobid

Nausea (8%)
Headache (6%)
Gas (2%)

Warnings for Macrobid

Lung damage
Liver damage
Nerve damage (neuropathy)
Breakdown of red blood cells (hemolytic anemia)
Severe diarrhea

Prices with our coupons for Blujepa vs. Macrobid

Blujepa20 tablets / 750mg

$1,830.25$2,274.83

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Nitrofurantoin14 capsules / 100mg

$15.73$46.26

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Blujepa vs. Macrobid

Blujepa

Nitrofurantoin

Summary for Blujepa

Indications for Blujepa

Pros and Cons for Blujepa

Pros

Cons

Common Side Effects for Blujepa

Warnings for Blujepa

Summary for Macrobid

Indications for Macrobid

Pros and Cons for Macrobid

Pros

Cons

Common Side Effects for Macrobid

Warnings for Macrobid

Prices with our coupons for Blujepa vs. Macrobid

Browse medications by letter

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Blujepa

Nitrofurantoin

Summary for Blujepa

Indications for Blujepa

Pros and Cons for Blujepa

Pros

Cons

Common Side Effects for Blujepa

Warnings for Blujepa

Summary for Macrobid

Indications for Macrobid

Pros and Cons for Macrobid

Pros

Cons

Common Side Effects for Macrobid

Warnings for Macrobid