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Bicillin CR vs. Bicillin L-A

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Bicillin CR

 

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Bicillin L-A

(penicillin G benzathine)

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Summary for Bicillin CR

Prescription only

Bicillin CR is a medication that contains two types of penicillin antibiotics. It's used to treat moderate-to-severe infections caused by streptococcus bacteria in people of all ages. These infections can happen in the throat (like strep throat), nose, lungs, skin, or soft tissues. Bicillin CR is given by a healthcare professional as an injection in your muscle. Bicillin CR can cause pain at the injection site as a side effect.

Indications for Bicillin CR

Pros and Cons for Bicillin CR

Pros

  • Good at fighting severe infections caused by strep bacteria
  • Works for many days in the body, so injections are given less often or even just once

Cons

Common Side Effects for Bicillin CR

  • Pain where the medication is injected
  • Inflammation or swelling where the medication is injected

Warnings for Bicillin CR

  • Serious or life-threatening problems when given incorrectly
  • Severe allergic reaction (anaphylaxis)
  • Severe skin reaction
  • Diarrhea from Clostridioides difficile infection
  • Methemoglobinemia (a type of blood problem)

Summary for Bicillin L-A

Prescription only

Bicillin L-A (penicillin G benzathine) is a medication used to treat a variety of bacterial infections including syphilis and strep throat. It's an antibiotic shot that's injected into your muscle (intramuscular). Depending on what you need it for, you might only need to receive it once. People of all ages can receive this antibiotic from a healthcare professional (HCP) at a hospital or clinic. The most common side effect is pain at the site of the injection.

Indications for Bicillin L-A

Pros and Cons for Bicillin L-A

Pros

  • First-choice antibiotic for syphilis
  • Might only need a single dose for treatment
  • A good choice if you can't take medications by mouth

Cons

  • Only available as a deep muscle injection, usually in the buttock or thigh
  • Typically needs to be given in a hospital or clinic
  • Can cause diarrhea like most other antibiotics

Common Side Effects for Bicillin L-A

  • Pain at the injection site

Warnings for Bicillin L-A

  • Deep muscle injection only
  • Severe allergic reaction (anaphylaxis)
  • Severe skin reactions
  • Severe diarrhea

Prices with our coupons for Bicillin CR vs. Bicillin L-A

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Bicillin CR1 package / 10 syringes of 1.2 million units per 2ml
$2,340.19$2,917.49
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Price Card Drug Icon
Bicillin L-A1 package / 10 syringes of 2.4 million units per 4ml
$8,790.47$9,480.39
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