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Compare Amiloride vs. Spironolactone

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Amiloride
    Spironolactone (Aldactone)
  • Amiloride
    Spironolactone (Aldactone)

  • Summary of Amiloride vs. Spironolactone

    Summary for Potassium-sparing diuretic
    Prescription only

    Amiloride is a potassium-sparing diuretics used to prevent low potassium levels in the blood when taken with certain medications that treat high blood pressure or heart failure. It comes in tablet form, taken by mouth once per day with food. Side effects include headache, nausea, and loss of appetite. While it's available as a generic, the brand name Midamor is no longer on the market.

    Summary for Potassium sparing diuretic
    Prescription only

    Spironolactone (Aldactone) is a type of potassium-sparing diuretic (water pill). It's used to treat heart failure, high blood pressure, and swelling from kidney or liver problems in adults. Because it blocks aldosterone (a hormone that affects sodium and potassium levels), spironolactone (Aldactone) can also treat conditions where there's too much aldosterone. Spironolactone (Aldactone) is taken by mouth, generally once or a few times a day, depending on your condition. Some common side effects of this medication include breast tenderness (males and females) and loss of libido (in males).

  • Indications of Amiloride vs. Spironolactone

    Indications for
    •To prevent low potassium levels in the blood when used with certain diuretic medications that treat high blood pressure and heart failure
    Indications for
    •Heart failure
    •High blood pressure
    •Swelling due to liver damage (cirrhosis)
    •Swelling due to nephrotic syndrome (a rare kidney condition) - tablets only
    •Primary aldosteronism (a hormone imbalance) - tablets only

  • Pros and Cons of Amiloride vs. Spironolactone

    Pros and Const for Potassium-sparing diuretic
    Pros
    •Helps prevent low potassium levels in people taking certain diuretics (water-pills)
    •Taken by mouth once per day
    Cons
    •Not a first-choice option for treating high blood pressure if used alone
    •Need regular blood tests to check potassium levels
    •Not the safest for people with kidney problems
    Pros and Const for Potassium sparing diuretic
    Pros
    •Taken by mouth
    •Oral suspension available for adults who've difficulty swallowing tablets
    •Lower-cost generics available
    Cons
    •Can make you urinate more often
    •Need to get blood tests regularly to check your electrolytes and kidney health
    •Can cause breast growth and lower sex drive in males

  • Common Side Effects of Amiloride vs. Spironolactone

    Common Side Effects for
    •Headache (up to 8%)
    •Nausea (up to 8%)
    •Loss of appetite (up to 8%)
    •Vomiting (up to 8%)
    •Diarrhea (up to 8%)
    Common Side Effects for
    •Dizziness
    •Headache
    •Sleepiness
    •Nausea
    •Vomiting
    •Diarrhea
    •Stomach cramps
    •Enlargement of male breasts
    •Breast pain
    •Lower sex drive
    •Sexual dysfunction
    •Irregular or lack of menstrual periods
    •Leg cramps
    •Higher potassium levels
    •Lower sodium levels

  • Warnings of Amiloride vs. Spironolactone

    Common Side Effects for
    •High potassium levels
    Common Side Effects for
    •High blood potassium levels
    •Low blood pressure and kidney problems
    •Abnormal electrolyte levels
    •Breast pain or swelling

  • Prices with our coupons for Amiloride vs. Spironolactone

    Learn more about Amiloride
    Learn more about Spironolactone

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