PDE3 inhibitors are used to treat worsened heart failure. They can also lessen symptoms of intermittent claudication (leg pain due to poor blood flow). Some also have other uses, such as treating certain blood conditions. These medications improve blood flow by blocking the enzyme phosphodiesterase 3 (PDE3), which helps to relax blood vessels and prevent platelets from clumping together. PDE3 inhibitors come in different forms, including oral tablets and injectable solutions. Examples include cilostazol, milrinone, and anagrelide (Agrylin). These treatments help manage your condition effectively.
