Farnesyltransferase inhibitors are used to manage certain rare genetic disorders, such as Hutchinson-Gilford Progeria Syndrome. These medications work by blocking the enzyme farnesyltransferase, which helps prevent the buildup of certain toxic proteins in the body. Farnesyltransferase inhibitors are typically available in oral form. An example includes Zokinvy (lonafarnib). You can take these medications as prescribed to help manage your condition.