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Apresazide
Hydralazine/hydrochlorothiazide is a combination medication used to lower blood pressure. It's no longer available in the United States because it was discontinued.
Last reviewed on December 1, 2021
What is Hydralazine/hydrochlorothiazide?
How Hydralazine/hydrochlorothiazide works
Drug Facts
Common BrandsApresazide (brand no longer available)
Drug ClassVasodilator / Diuretic
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
Frequently asked questions about Hydralazine/hydrochlorothiazide
What is hydralazine/hydrochlorothiazide?
Hydralazine/hydrochlorothiazide is made up of two medications that both lower your blood pressure. Hydralazine is a vasodilator that relaxes blood vessels, causing them to open up (dilate). Hydrochlorothiazide, or HCTZ, is a thiazide diuretic (water pill) that works in the kidneys to remove extra water, which lowers blood pressure and gets rid of swelling.
Is hydralazine/hydrochlorothiazide still available?
No, hydralazine/hydrochlorothiazide has been discontinued and is no longer available in the United States.
Why was hydralazine/hydrochlorothiazide discontinued?
It's not clear why hydralazine/hydrochlorothiazide has been discontinued. Both of the active ingredients in hydralazine/hydrochlorothiazide are still available as single-ingredient medications (hydralazine and hydrochlorothiazide (Microzide)). These single-ingredient medications are still commonly used today for high blood pressure (hydralazine and HCTZ) and water retention (swelling) in the body (HCTZ only).
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