Is hydralazine/hydrochlorothiazide still available?

No, hydralazine/hydrochlorothiazide has been [discontinued](https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=084810) and is no longer available in the United States.

Why was hydralazine/hydrochlorothiazide discontinued?

It's not clear why hydralazine/hydrochlorothiazide has been [discontinued](https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=084810). Both of the active ingredients in hydralazine/hydrochlorothiazide are still available as single-ingredient medications ([hydralazine](https://www.goodrx.com/hydralazine/what-is) and [hydrochlorothiazide (Microzide)](https://www.goodrx.com/hydrochlorothiazide/what-is)). These single-ingredient medications are still commonly used today for high blood pressure (hydralazine and HCTZ) and water retention (swelling) in the body (HCTZ only).

Apresazide

hydralazine / hydrochlorothiazide

Used for Hypertension

Basics FAQs Dosage Prices Medicare

Hydralazine/hydrochlorothiazide is a combination medication used to lower blood pressure. It's no longer available in the United States because it was discontinued.

Reviewed by:

Robert Chad Hakim, PharmD, BCCCP

Cydnee Ng, PharmD

Last reviewed on December 1, 2021

Basics FAQs Dosage Prices Medicare

What is Hydralazine/hydrochlorothiazide?

Drug facts

Common BrandsApresazide(brand no longer available)

Drug ClassVasodilator / Diuretic

Controlled Substance ClassificationNot a controlled medication

Generic StatusNo lower-cost generic available

AvailabilityDiscontinued

Common questions about Hydralazine/hydrochlorothiazide

Hydralazine/hydrochlorothiazide is made up of two medications that both lower your blood pressure. Hydralazine is a vasodilator that relaxes blood vessels, causing them to open up (dilate). Hydrochlorothiazide, or HCTZ, is a thiazide diuretic (water pill) that works in the kidneys to remove extra water, which lowers blood pressure and gets rid of swelling.

No, hydralazine/hydrochlorothiazide has been discontinued and is no longer available in the United States.

It's not clear why hydralazine/hydrochlorothiazide has been discontinued. Both of the active ingredients in hydralazine/hydrochlorothiazide are still available as single-ingredient medications (hydralazine and hydrochlorothiazide (Microzide)). These single-ingredient medications are still commonly used today for high blood pressure (hydralazine and HCTZ) and water retention (swelling) in the body (HCTZ only).