Is chlorothiazide/methyldopa still available?

No, chlorothiazide/methyldopa has been [discontinued](https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=016016) and is no longer available in the United States. It's not clear why chlorothiazide/methyldopa was discontinued.

Are there currently available medications that are used in place of chlorothiazide/methyldopa?

Yes. While the combination medication has been discontinued, both chlorothiazide and methyldopa are still available as single-ingredient medications. Although [methyldopa](https://www.goodrx.com/methyldopa/what-is) isn't commonly used today, [chlorothiazide (Diuril)](https://www.goodrx.com/chlorothiazide/what-is) is one of many [available medications that works well for the treatment of high blood pressure](https://www.goodrx.com/conditions/hypertension/high-blood-pressure-medications). Ask your provider about other options to treat high blood pressure that are right for you.

Aldoclor

Q: What is chlorothiazide/methyldopa?

Chlorothiazide/methyldopa is made up of two medications that lower your blood pressure. __Chlorothiazide__ is a [thiazide diuretic](https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/1108565) (water pill) that [works in the kidneys](https://www.ahajournals.org/doi/10.1161/01.cir.26.1.121) to remove extra water, which lowers blood pressure and gets rid of swelling. __Methyldopa__ is an [alpha-2 adrenergic receptor agonist](https://www.ncbi.nlm.nih.gov/books/NBK551671/#article-25081.s3) that works by telling the brain to lower the activity of stress hormones. Fewer stress hormones leads to more relaxed blood vessels, which lowers blood pressure.

chlorothiazide / methyldopa

Used for Hypertension

Chlorothiazide/methyldopa is a combination medication used to lower blood pressure. It's no longer available in the United States, because it was discontinued.

Reviewed by:

Robert Chad Hakim, PharmD, BCCCP

Allison Gourley, PharmD

Last reviewed on June 27, 2022

What is Chlorothiazide/methyldopa?

What is Chlorothiazide/methyldopa used for?

High blood pressure

Are you looking for information on chlorothiazide (Diuril), hydrochlorothiazide (Microzide), or methyldopa instead?

Drug facts

Common Brands	Aldoclor(brand no longer available)
Drug Class	Diuretic / Alpha-2 adrenergic receptor agonist
Controlled Substance Classification	Not a controlled medication
Generic Status	No lower-cost generic available
Availability	Discontinued

Common Brands

Aldoclor(brand no longer available)

Drug Class

Diuretic / Alpha-2 adrenergic receptor agonist

Controlled Substance Classification

Not a controlled medication

Generic Status

No lower-cost generic available

Availability

Discontinued

Common questions about Aldoclor

Aldoclor is made up of two medications that lower your blood pressure. Chlorothiazide is a thiazide diuretic (water pill) that works in the kidneys to remove extra water, which lowers blood pressure and gets rid of swelling. Methyldopa is an alpha-2 adrenergic receptor agonist that works by telling the brain to lower the activity of stress hormones. Fewer stress hormones leads to more relaxed blood vessels, which lowers blood pressure.

No, Aldoclor has been discontinued and is no longer available in the United States. It's not clear why Aldoclor was discontinued.

Yes. While the combination medication has been discontinued, both chlorothiazide and methyldopa are still available as single-ingredient medications. Although methyldopa isn't commonly used today, chlorothiazide (Diuril) is one of many available medications that works well for the treatment of high blood pressure. Ask your provider about other options to treat high blood pressure that are right for you.