The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Common hydrochlorothiazide side effects:
- Weakness
- Low blood pressure
- Diarrhea
- Vomiting
- Low electrolyte levels (e.g., calcium, magnesium, sodium)
Common spironolactone side effects:
- Fatigue
- Dizziness
- Headache
- Breast pain or tenderness
- Muscle cramps
- High potassium levels
Less Common Side Effects
- Difficulty getting or maintaining an erection
- Low sex drive
- Irregular or no menstrual periods
- Leg cramps
- Dehydration
Aldactazide serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic reaction or skin reaction: sore throat, fever, fatigue, rash, hives, painful blisters, skin reddening, skin peeling, swollen lymph nodes
- High potassium levels: nausea, muscle weakness, tingling, abnormal heartbeat
- Abnormal levels of other electrolytes: muscle cramps, fainting, irregular heartbeat, seizure
Source: DailyMed
The following Aldactazide side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Incidence not known
Back or leg pains
blistering, peeling, or loosening of the skin
bloody or black, tarry stools
bloody or cloudy urine
blue lips and fingernails
blurred vision
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
chest pain or tightness
clay-colored stools
clear or bloody discharge from the nipple
confusion
cough or hoarseness
dark urine
decreased appetite
difficult, fast, or noisy breathing
difficulty with swallowing
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fast or irregular heartbeat
fever with or without chills
flushed, dry skin
fruit-like breath odor
general body swelling
general feeling of discomfort or illness
greatly decreased frequency of urination or amount of urine
hives or welts, skin rash
increased hunger
increased thirst
inverted nipple
joint pain, stiffness, or swelling
lower back or side pain
lump in the breast or under the arm
muscle cramps or pain
numbness, tingling, pain, or weakness in the hands, feet, or lips
painful or difficult urination
pains in the stomach, side, or abdomen, possibly radiating to the back
persistent non-healing sore
pink growth
pinpoint red or purple spots on the skin
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
red, irritated eyes
reddish patch or irritated area
redness or swelling of the breast
redness, soreness, or itching skin
seizures
shiny bump
sore on the skin of the breast that does not heal
sores, ulcers, or white spots on the lips or in the mouth
stomach cramping, burning, or tenderness
swelling of the face, hands, fingers, feet, or lower legs
swollen, painful, or tender lymph glands in the neck, armpit, or groin
trembling
trouble breathing
unusual bleeding or bruising
unusual tiredness or weakness
white, yellow or waxy scar-like area
yellow eyes or skin
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
Difficulty with sleeping
disorientation
drowsiness to profound coma
hallucination
lethargy
lightheadedness
mood or other mental changes
rash with flat lesions or small raised lesions on the skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
Absent, missed, or irregular menstrual periods
burning feeling in the chest or stomach
discoloration of the skin
feeling of constant movement of self or surroundings
inability to have or keep an erection
increased sensitivity of the skin to sunlight
restlessness
sensation of spinning
severe sunburn
stomach upset
stopping of menstrual bleeding
swelling of the breasts or breast soreness in both females and males
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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