Tamsulosin is an alpha-1 blocker used to treat benign prostatic hyperplasia (BPH), also known as enlarged prostate. It works by relaxing the muscles in your prostate and bladder, making it easier to urinate. The medication comes as a capsule that you take once a day, usually 30 minutes after the same meal each day. Side effects include headache, dizziness, and abnormal ejaculation.
Enlarged prostate (benign prostatic hyperplasia or BPH)
Tamsulosin is an alpha-1 blocker. It specifically targets alpha-1 receptors in the prostate. By blocking these receptors, the medication relaxes the muscles in your prostate and bladder. This makes it easier to urinate and helps to relieve symptoms of BPH.
Source: DailyMed
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Less common
Rare
Dizziness or lightheadedness
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fainting
feeling of constant movement of self or surroundings
painful or prolonged erection of the penis
sensation of spinning
Incidence not known
Blistering, peeling, or loosening of the skin
blurred vision
confusion
difficult or labored breathing
fast, pounding, or irregular heartbeat or pulse
joint or muscle pain
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
red skin lesions, often with a purple center
red, irritated eyes
sores, ulcers, or white spots in the mouth or on the lips
sweating
tightness of the chest
unusual tiredness or weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Abnormal ejaculation
back pain
body aches or pain
congestion
headache
lack or loss of strength
stuffy or runny nose
tender, swollen glands in the neck
trouble swallowing
voice changes
Less common
Decreased interest in sexual intercourse
decreased sexual drive or performance
drowsiness
inability to have or keep an erection
increased cough
loss in sexual ability, desire, drive, or performance
pain or tenderness around the eyes and cheekbones
sleepiness or unusual drowsiness
tooth disorder
trouble sleeping
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Is a first-choice treatment option for BPH
Taken by mouth once a day
Typically starts to work right away
Less likely to cause a sudden drop in blood pressure when changing positions compared to similar medications
Relieves symptoms of an enlarged prostate but doesn’t affect prostate growth
Needs to be taken once a day, 30 minutes after the same meal
Can have negative side effects on your sexual health
Might not be the best option for people with a sulfa allergy
Take tamsulosin 30 minutes after the same meal every day. This will help your body absorb the right amount of medication.
Swallow tamsulosin capsules whole. Don't crush, chew, or open them because it will affect how the medication works.
If you miss a dose of tamsulosin, take it as soon as you remember the same day. If you don’t remember until the next day, just take your next dose at your regular schedule. Never take two doses at the same time.
If you stop taking tamsulosin for several days in a row, talk with your prescriber before you start taking it again since your dose might be different.
Tamsulosin can cause dizziness and low blood pressure, especially when you get up too quickly. To lower this risk, move slowly when going from lying down to sitting, and then from sitting to standing.
If you’re an older adult, you might experience more dizziness while taking tamsulosin. These side effects can raise the risk of falls and broken bones. Let your prescriber know if you feel very dizzy or faint.
It's best not to drink alcohol while taking tamsulosin. Alcohol can worsen low blood pressure, especially when changing positions.
Tamsulosin interacts with a lot of commonly used medications. Tell your care team about all the medications you're taking so they can make sure it's safe.
Tamsulosin can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Risk factors: Moving too quickly from sitting down to standing up | Not enough fluid in your body (dehydration) | Taking other medications that lower blood pressure | Heart failure | Drinking alcohol
When you first start tamsulosin or when your dose is raised, you can experience a sudden drop in blood pressure when standing or sitting up too quickly. This is called orthostatic hypotension. To lower this risk, move slowly from lying down to sitting, and then stand up slowly. Symptoms include feeling lightheaded or dizzy, blurry vision, fainting, nausea, or confusion. Your body should adjust to the medication after the first few days. But if these symptoms continue, tell your prescriber. If you fall and hit your head, get medical help right away.
Tamsulosin can interact with many medications. Certain medications like ketoconazole, erythromycin, or paroxetine can raise your risk of side effects.
Be especially careful if you’re also taking certain erectile dysfunction medications (like sildenafil, tadalafil, or vardenafil), because taking them together with tamsulosin can cause dizziness, fainting, or other symptoms of low blood pressure. Always tell your prescriber about all the medications you take so they can check for interactions.
Although rare, tamsulosin has been linked to priapism, which is a painful erection that lasts for hours and isn’t related to sexual activity. This condition is very serious because it can cause permanent erectile problems if not treated right away. If you develop an erection that lasts longer than 4 hours, stop taking tamsulosin and get medical attention right away.
Risk factors: Planned cataract or glaucoma surgery
Tamsulosin can cause an eye problem called intraoperative floppy iris syndrome (IFIS), which can happen during cataract or glaucoma surgery. IFIS can make the surgery harder and raise your risk of eye problems afterwards, and it can happen even if you’ve already stopped taking the medicine. Let your optometrist or ophthalmologist know if you take or have ever taken tamsulosin because they might change their surgical technique to lower your risk for IFIS.
Risk factors: Sulfa allergy
If you have a sulfa allergy, there’s a small chance you could have an allergic reaction to tamsulosin. This is rare, but if your sulfa allergy has ever been serious or life-threatening, let your prescriber know.
| Dosage | Quantity | Price as low as | Price per unit | 
|---|---|---|---|
| 0.4mg | 30 capsules | $4.80 | $0.16 | 
The typical starting dose is 0.4 mg by mouth once a day, 30 minutes after the same meal each day.
GoodRx has partnered with PatientsLikeMe to provide reviews on the different aspects of Tamsulosin.
Learn more about the effectiveness of Tamsulosin based on real life experiences.
Based on 75 people taking this medication
2.6
3.0
2.7
1.9
1.9
3.8
Severity of side effects
Based on 187 people taking this medication
0%
50%
100%
Lightheadedness
4%
Ejaculation dysfunction
2%
Dizziness
2%
Dizziness with hypotension upon standing
2%
Ejaculation delayed
2%
Reasons people stopped taking Tamsulosin
Based on 120 people who have taken this medication
Course of treatment ended
26%
Did not seem to work
22%
Doctor's advice
22%
Other
15%
Side effects too severe
11%
Expense
3%
Personal research
2%
Change in health plan coverage
1%
How long people take Tamsulosin
Based on 402 people taking this medication
0%
50%
100%
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Enlarged prostate (benign prostatic hyperplasia or BPH)
Signs and symptoms of benign prostatic hyperplasia (BPH)
Enlarged prostate (benign prostatic hyperplasia, BPH)
High blood pressure - immediate-release tablet only
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Ascend Laboratories, LLC. (2025). TAMSULOSIN HYDROCHLORIDE capsule [package insert]. DailyMed.
Chapple, C. R. (2005). A comparison of varying α-blockers and other pharmacotherapy options for lower urinary tract symptoms. Reviews in Urology.
Höfner, K., et al. (1999). Tamsulosin 0.4 mg once daily: Effect on sexual function in patients with lower urinary tract symptoms suggestive of benign prostatic obstruction. European Urology.
Lowe, F. C. (2005). Summary of Clinical Experiences With Tamsulosin for the Treatment of Benign Prostatic Hyperplasia. Reviews in Urology.
Moussa, A. S., et al. (2019). Predictive value of the immediate effect of first dose of tamsulosin on lower urinary tract symptoms improvement in benign prostatic hyperplasia patients. Urology Annals.
Nachawati, D., et al. (2025). Alpha-Blockers. StatPearls.
Paśko, P., et al. (2016). Interactions between medications employed in treating benign prostatic hyperplasia and food − A short review. Biomedicine & Pharmacotherapy.
Sandhu, J. S., et al. (2024). Management of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia (BPH): AUA Guideline Amendment 2023. American Urological Association.
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