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Raplixa

fibrin sealant
Used for Hemorrhage

Raplixa is a topical medication that's used on the outside of the body. It's used along with other methods during surgery to help stop bleeding. This medication comes in the form of a dry powder and can be used together with a gelatin sponge. Raplixa has been discontinued by the manufacturer and is no longer available in the United States.

Reviewed by:Last reviewed on June 19, 2022
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What is Raplixa?

What is Raplixa used for?

  • Stop bleeding in adults during surgery

Drug facts

Common BrandsRaplixa(brand no longer available)
Drug ClassAntihemorrhagic
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
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Common questions about Raplixa

Raplixa is a medication that's used to help stop mild-to-moderate bleeding in adults during surgery. It's typically used as an alternative option to common surgical methods to stop bleeding, such as suture (the string used to stitch up a wound) or cautery (a practice that burns off tissue to stop bleeding). Raplixa is a fibrin sealant that contains two important proteins that naturally help your blood clot. When this medication is used on a wound, it activates the blood-clotting process and stops bleeding.

No, Raplixa has been discontinued and is no longer available in the United States.

The company who owns Raplixa (Mallinckrodt) voluntarily discontinued the medication in 2017 for business reasons. It wasn't taken off the market for safety concerns or lack of benefit.

Some alternative treatments to Raplixa that can help stop bleeding during surgery are Vivostat, CryoSeal, and Tisseel. There are many differences between these three alternatives, and research suggests Tisseel might work the best. But, you might respond better to one medication versus another. There are also other methods to stop bleeding during surgery. Your surgeon will determine which method is best for you. Talk to your provider so you can discuss the benefits and risks of the different options.

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Raplixa dosage

Typical dosage for Raplixa

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