The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Nausea
- Vomiting
- Upper stomach pain or tenderness
- Joint pain
- Itching
- Tingling sensation
- Loss or change in taste
- Loss of hair
- Muscle pain
- Headache
- Nerve pain
- Swelling (edema)
- Dizziness
Less Common Side Effects
- Skin rash
- Skin discoloration
- Vertigo
- Yellowing of the whites of the eyes
Propylthiouracil serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Low white blood cells: fever, chills, cough, muscle aches
- Liver damage: nausea, stomach pain, clay-colored stools, yellow skin or whites of your eyes
- Bleeding: blood in stools, pink urine, unexplained or excessive bruising
- Severe skin reaction: blisters, peeling skin, red skin, rash
Source: DailyMed
The following Propylthiouracil side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Black, tarry stools
chills
painful or difficult urination
shortness of breath
sores, ulcers, or white spots on the lips or in the mouth
swollen glands
unusual bleeding or bruising
unusual tiredness or weakness
Less common
Dark-colored urine
general feeling of discomfort, illness, or weakness
headache
light-colored stools
nausea or vomiting
stomach pain, continuing
upper right abdominal or stomach pain
yellow eyes and skin
Incidence not known
Abdominal or stomach pain
agitation
bleeding gums
bleeding under the skin
blood in the urine or stools
bloody or cloudy urine
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
coma
confusion
cough or hoarseness
cracks in the skin
decreased urine output
difficulty with breathing
difficulty with moving
dizziness
drowsiness
feeling of fullness
fever with or without chills
general feeling of discomfort, illness, or weakness
hostility
irritability
joint pain
lethargy
loss of appetite and weight
loss of heat from the body
lower back or side pain
muscle aching or cramping
muscle pain or stiffness
muscle twitching
numbness or tingling of the hands, feet, or face
pain in the ankles or knees
painful, red lumps under the skin, mostly on the legs
pinpoint red spots on the skin
rapid weight gain
red, swollen skin
redness, soreness, or itching skin
seizures
soreness of the muscles
sores on the skin
sores, ulcers, or white spots on the lips or in the mouth
sores, welting, or blisters
stupor
swelling of the face, ankles, hands, feet, or lower legs
swollen joints
swollen salivary glands
swollen, painful, or tender lymph glands in the neck, armpit, or groin
tightness in the chest
unusual weight gain
Get emergency help immediately if any of the following symptoms of overdose occur:
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
Abnormal loss of hair
change in taste or bad unusual or unpleasant (after) taste
dizziness or lightheadedness
feeling of constant movement of self or surroundings
hives or welts
loss of taste
pain or discomfort in the chest, upper stomach, or throat
sensation of spinning
skin rash
sleepiness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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