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Metyrosine

Metyrosine Side Effects

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

These side effects occurred in at least 10% of people taking the medication:

  • Drowsiness
  • Drooling
  • Difficulty speaking
  • Shakiness
  • Diarrhea

Less Common Side Effects

  • Anxiety
  • Depression
  • Confusion
  • Stuffy nose
  • Dry mouth
  • Headache
  • Enlarged breasts
  • Nausea
  • Stomach pain
  • Difficulty getting or maintaining an erection
  • Painful urination

Metyrosine serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Mental health changes: depression, hallucinations (seeing things that aren't there), confusion
  • Extrapyramidal symptoms (EPS): drooling, trouble speaking, tremor, muscle spasms, tightness in your jaw
  • Low blood cell counts: feeling tired, paleness, blood in urine or stool, unexplained bruising
  • Severe allergic reaction: hives, swelling in the throat, trouble breathing
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Source: DailyMed

The following Metyrosine side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

Diarrhea

drooling

trembling and shaking of hands and fingers

trouble in speaking

Less common

Anxiety

confusion

hallucinations (seeing, hearing, or feeling things that are not there)

mental depression

Rare

Black, tarry stools

blood in urine or stools

unusual bleeding or bruising

muscle spasms, especially of neck and back

painful urination

pinpoint red spots on skin

restlessness

shortness of breath

shuffling walk

skin rash and itching

swelling of feet or lower legs

tic-like (jerky) movements of head, face, mouth, and neck

unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Drowsiness

Less common

Decreased sexual ability in men

dryness of mouth

nausea, vomiting, or stomach pain

stuffy nose

swelling of breasts or unusual milk production

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

More common

Diarrhea

Also, after you stop taking this medicine, you may have feelings of increased energy or you may have trouble sleeping. However, these effects should last only for two or three days.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Kristianne Hannemann, PharmD, is a licensed pharmacist in California. She has been a retail pharmacy manager and staff pharmacist for over 7 years and has contributed drug information content to different health companies.
Before embarking on her journey in pharmacy, Kieu-My honed her skills as a researcher at Stanford University, delving deep into scientific exploration to advance healthcare. This experience instilled in her a profound love for science and a desire to bridge the gap between scientific knowledge and patient care, ultimately maximizing the benefits for all those in need.

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