What is Meprobamate?

Commonly Used Brand Name(s)Mb-Tab, Miltown, Trancot

Therapeutic ClassificationsAntianxiety

OverviewTOP

Meprobamate is used to relieve nervousness or tension. This medicine should not be used for nervousness or tension caused by the stress of everyday life.

Meprobamate is available only with your doctor's prescription.

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Proper UseTOP

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much is taken, it may become habit-forming.

DosingTOP

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For regular (short-acting) tablets:
- Adults and children 12 years of age and older: 400 milligrams three or four times a day, or 600 milligrams two times a day.
- Children 6 to 12 years of age: 100 to 200 milligrams two or three times a day.
- Children up to 6 years of age: Dose must be determined by the doctor.
For long-acting dosage forms (extended-release tablets):
- Adults and children 12 years of age or older: 400 to 800 milligrams two times a day, in the morning and at bedtime.
- Children 6 to 12 years of age: 200 milligrams two times a day, in the morning and at bedtime.
- Children up to 6 years of age: Dose must be determined by the doctor.

Missed DoseTOP

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Use & StorageTOP

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Before UsingTOP

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

AllergiesTOP

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

PediatricTOP

Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of meprobamate in children with use in other age groups.

GeriatricTOP

Elderly people may be especially sensitive to the effects of meprobamate. This may increase the chance of side effects during treatment.

Breast FeedingTOP

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug InteractionsTOP

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Alfentanil
Alprazolam
Amobarbital
Aprobarbital
Benzhydrocodone
Bromazepam
Bromopride
Buprenorphine
Butabarbital
Butalbital
Butorphanol
Carbinoxamine
Carisoprodol
Chloral Hydrate
Chlordiazepoxide
Chlorzoxazone
Clobazam
Clonazepam
Clorazepate
Codeine
Dantrolene
Diazepam
Dihydrocodeine
Doxylamine
Eslicarbazepine Acetate
Estazolam
Ethchlorvynol
Fentanyl
Flibanserin
Fluconazole
Flunitrazepam
Flurazepam
Fospropofol
Halazepam
Hydrocodone
Hydromorphone
Ketazolam
Levorphanol
Lofexidine
Lorazepam
Lormetazepam
Loxapine
Meclizine
Medazepam
Meperidine
Mephenesin
Mephobarbital
Meprobamate
Metaxalone
Methadone
Methocarbamol
Methohexital
Metoclopramide
Midazolam
Morphine
Morphine Sulfate Liposome
Nalbuphine
Nitrazepam
Oxazepam
Oxycodone
Oxymorphone
Pentazocine
Pentobarbital
Periciazine
Phenobarbital
Prazepam
Primidone
Propofol
Quazepam
Remifentanil
Secobarbital
Sodium Oxybate
Sufentanil
Tapentadol
Temazepam
Thiopental
Tramadol
Triazolam
Zolpidem

Other InteractionsTOP

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

PrecautionsTOP

If you will be taking this medicine regularly for a long time:

Your doctor should check your progress at regular visits.
Check with your doctor at least every 4 months to make sure you need to continue taking this medicine.

If you will be taking this medicine in large doses or for a long time, do not stop taking it without first checking with your doctor. Your doctor may want you to reduce gradually the amount you are taking before stopping completely.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that slow down the nervous system, possibly causing drowsiness). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are taking this medicine.

Before you have any medical tests, tell the medical doctor in charge that you are taking this medicine. The results of some tests, such as the metyrapone test and the phentolamine test, may be affected by this medicine.

If you think you or someone else may have taken an overdose of this medicine, get emergency help at once. Taking an overdose of meprobamate or taking alcohol or other CNS depressants with meprobamate may lead to unconsciousness and possibly death. Some signs of an overdose are severe confusion, drowsiness, or weakness; shortness of breath or slow or troubled breathing; slurred speech; staggering; and slow heartbeat.

This medicine may cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally. Even if taken at bedtime, it may cause some people to feel drowsy or less alert on arising. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert .

Meprobamate may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.

Chemical ClassificationsTOP

Carbamate