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Eroxon

glyceryl trinitrate
Used for Erectile Dysfunction
Used for Erectile Dysfunction

Eroxon is the first over-the-counter (OTC) gel that's used to treat erectile dysfunction (ED) in males 22 years and older. As an FDA-cleared product, it doesn't contain medication. The gel is applied directly to the head of the penis before sexual activity and starts working within 10 minutes. Side effects include burning or itching where it’s applied.

Reviewed by:
reviewer
Kristianne Hannemann, PharmD
reviewer
Daisy Chau, PharmD
Last reviewed on December 11, 2024
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageAlternativesLatest newsReferencesPricesMedicare
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What is Eroxon?

What is Eroxon used for?

How Eroxon works

Eroxon is a topical nitrate. When applied to the penis, it stimulates nerve endings. This helps more blood flow into the penis, which causes an erection.

Drug Facts

Common BrandsEroxon
Drug ClassMedical device
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityOver-the-counter

More on Eroxon essentials

eroxon: man using mobile phone in bed 1195095517

What Is Eroxon Gel? Answers to 8 FAQs About This OTC Erectile Dysfunction Gel

Written by Austin Ulrich, PharmD, BCACP
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What are the side effects of Eroxon?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Headache (3%)
  • Burning sensation at application site (1%)

Other Side Effects

  • Itching at application site

Source: Haleon

pros-and-cons

Pros and cons of Eroxon

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Pros

Applied directly to the penis where it works

Works within 10 minutes for most people

Doesn't require a prescription

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Cons

Doesn't protect against sexually transmitted infections (STIs)

Might cause burning or itching after applying it

Not studied in males younger than 22 years old

pharmacist-tips

Pharmacist tips for Eroxon

pharmacist

  • Eroxon works best when used together with sexual stimulation. Only apply the gel right before sexual activity.

    • To use Eroxon, squeeze the full amount out of one tube onto your finger and massage it onto the head of your penis for 15 seconds. You or your partner can apply the gel.

      • If you're uncircumcised, pull back the foreskin gently before applying Eroxon.

        • You can use Eroxon with lubricants and most condoms (latex and polyisoprene). But don't use it with polyurethane condoms since the gel isn't compatible with them.

          • If Eroxon doesn't work the first time, wait and try to use it again at another time. You might need to try it 3 or 4 times before you get the results you want. Be sure to use all the gel in the tube each time for the right dose.

            • You or your partner might feel some burning and itching after using Eroxon. If these symptoms don't go away or become uncomfortable, speak to a healthcare professional.

              faqs

              Frequently asked questions about Eroxon

              How fast does Eroxon work?
              Eroxon can start working within 10 minutes of applying it, but results can vary from person to person and even between uses. If you don’t get the results you want after one tube, try using the gel again at a different time. It might take a few tries to get the desired effect.
              Where can I buy Eroxon?
              You can buy Eroxon online or at many pharmacies and retailers. The product is available over the counter and doesn't require a prescription.
              Does Eroxon really work?
              In two studies, around 60% of males with erectile dysfunction experienced improved erections. Talk to your primary care provider if you have questions about whether this product will work for you.
              Can I use condoms with Eroxon?
              Condoms made with latex and polyisoprene are safe to use with Eroxon. Avoid polyurethane condoms since the gel isn't compatible with them.
              How long does Eroxon keep you erect?
              Eroxon lasts for one session of penetrative sex. If it doesn’t seem to last long enough, don’t use more than one tube at a time. Instead, talk to a healthcare professional about other treatment options.
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              What are the risks and warnings for Eroxon?

              Eroxon can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

              risk-warning

              Irritation

              Stop using Eroxon if you experience burning, itching, or redness after applying it. If the irritation doesn't seem to be getting better, contact your primary care provider.

              dosage

              Eroxon dosage forms

              Typical dosing for Eroxon

              Apply one full tube of gel to the head of the penis before sexual activity.

              alternatives

              What are alternatives to Eroxon?

              There are a number of medications that your doctor can prescribe in place of Eroxon. Compare a few possible alternatives below.
              Eroxon
              Used for:
              View Prices
              Sildenafil (Viagra)
              Used for:

              • Erectile dysfunction (ED)

              $12.56 Lowest GoodRx priceView Prices
              Stendra (avanafil)
              Used for:
              $162.40 Lowest GoodRx priceView Prices

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              References

              Best studies we found

              Haleon. (n.d.). Frequently asked questions about ED.

              Haleon. (2024). Eroxon® [package insert].

              Hellstrom, W. J. G., et al. (2024). PD52-07 Efficacy and safety of MED3000, a novel topical therapy for the treatment of erectile dysfunction. Journal of Urology.

              GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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