Skip to main content

Cold Sores Medications

Find prices and information on Cold Sores medications.

Read our guide toCold Sores

Key takeaways

Medications for cold sores are used to treat herpes labialis (cold sores), a type of herpes simplex virus (HSV) infection. These medications also have other uses, such as managing genital herpes. They work by stopping the virus from multiplying, which helps to reduce symptoms and speed up healing. Common classes include antiviral medications. Medications like valacyclovir (Valtrex) and famciclovir (Famvir) are taken orally, while acyclovir is available in both oral tablet and topical dosage forms. Topical treatments like penciclovir (Denavir) and docosanol (Abreva) are applied directly to the cold sore. Xerese is a combination cream that contains acyclovir and hydrocortisone to both prevent the spread of infection and decrease symptoms such as redness and swelling. These medications offer various ways to help manage and treat your cold sores effectively.

Prices for popular Cold Sores medications
Viewing 7 of 7 medications
Valacyclovir (Valtrex) is an antiviral medicine. It is used to treat or prevent infections caused by certain kinds of viruses. Examples of these infections include herpes and shingles.This medicine will not cure herpes. It is more popular than comparable drugs. It is available in generic and brand versions. Generic valacyclovir is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Acyclovir (Zovirax) is an inexpensive drug used to treat or prevent infections caused by certain kinds of viruses. Examples of these infections include herpes and shingles. This drug is slightly more popular than comparable drugs. It is available in generic and brand form. Generic acyclovir is covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
DOCOSANOL helps manage infections, such as cold sores, caused by viruses. It works by reducing how long your symptoms last. It does not kill the virus and it may still be possible to spread the virus to others. It will not treat infections caused by bacteria.
FAMCICLOVIR helps manage infections, such as cold sores and genital herpes, caused by viruses. This medication does not kill the virus and it may still be possible to spread the virus to others. It will not treat colds, the flu, or infections caused by bacteria.
PENCICLOVIR helps manage infections, such as cold sores, caused by viruses. This medication does not kill the virus and it may still be possible to spread the virus to others. It belongs to a group of medications called antivirals.
dose-pack icon

Sitavig

as low as$920
ACYCLOVIR helps manage infections, such as cold sores, caused by viruses. This medication does not kill the virus and it may still be possible to spread the virus to others. This medication will not treat colds, the flu, or infections caused by bacteria.
tube-of-cream icon

Xerese

as low as$1,183
ACYCLOVIR; HYDROCORTISONE helps manage infections, such as cold sores, caused by viruses. It also decreases inflammation. This medication does not kill the virus and it may still be possible to spread the virus to others. It will not treat colds, the flu, or infections caused by bacteria.
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

Subscribe and save

Get prescription saving tips and more from GoodRx Health. Enter your email to sign up

By providing your email, you consent to receive marketing communications from GoodRx, which may include content and/or data related to men's health, women's health, reproductive care, or sexual health. You agree to the GoodRx Terms of Use and acknowledge the Privacy Policy. You can unsubscribe at any time.

Latest Articles

Browse medications

View All
Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.