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Zelsuvmi vs. Ycanth

Zelsuvmi (berdazimer) is a topical gel used to treat a viral skin infection called molluscum contagiosum (MC). It’s approved for adults and children 1 year or older. This medication works as a nitric oxide-releasing agent to fight the virus and remove the small MC bumps (lesions) on your skin. Zelsuvmi (berdazimer) comes in two separate gel tubes that you mix together right before applying. You apply the gel directly to the skin lesions once a day for up to 12 weeks. Side effects include pain, redness, and itching at the application site.

• Molluscum contagiosum in adults and children ages 1 year or older

• Pain (such as burning or stinging, 19%)
• Redness (12%)
• Itching (6%)
• Peeling or flaking (5%)
• Itchy, dry skin rash (5%)

• Skin reactions

Ycanth (cantharidin) is a solution that’s applied on your skin to treat a skin infection called molluscum contagiosum. This medication can be used on adults and children, though the infection is most commonly seen in children under 10 years old. Your provider will apply Ycanth (cantharidin) directly to the wart-like rash or bumps on the skin (also known as lesions) that’s caused by the infection. You’ll go to the provider’s office for treatment once every 3 weeks, typically for up to 4 treatments or as instructed by your provider. Some common side effects of Ycanth (cantharidin) include blistering, pain, or itching at the application site.

• Molluscum contagiosum in adults and children ages 2 years and older

Application site reactions:

• Blistering (up to 60%)
• Itching (up to 47%)
• Pain (up to 41%)
• Scabbing (up to 39%)
• Discoloration (up to 28%)
• Redness (up to 24%)

• Serious toxicities (from accidental contact with mouth or eyes)
• Skin reactions at or near the treated area
• Risk of fires