Trifluridine
(Viroptic)
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Summary for Trifluridine
Trifluridine (Viroptic) is an antiviral eye drop that treats inflammation caused by herpes infections in the eye. It's FDA approved for people 6 years and older. When you first start, the eye drops need to be used frequently, every 2 hours while you're awake, with a maximum of 9 drops per day. This medication comes in both brand-name and generic versions. The most common side effects include temporary burning or stinging when you apply the eye drops to your eye(s).
Indications for Trifluridine
- Inflammation caused by herpes infections in the eye
Pros and Cons for Trifluridine
Pros
- Works well to treat a herpes eye infection by helping the eye heal
- Most side effects are mild and temporary
- Proven safe and effective in children as young as 6 years old
Cons
- Must be used multiple times a day
- Can't be used long-term since doing so can cause eye injury
- Doesn't treat infections caused by bacteria, fungi, or other viruses
Common Side Effects for Trifluridine
- Mild, temporary burning or stinging (5%)
- Eyelid swelling (3%)
Warnings for Trifluridine
- Damage to eyes from long-term use
- Only for herpes eye infection
- Eye irritation
Summary for Erythromycin
Erythromycin is an antibiotic that's used to treat a variety of infections caused by bacteria, including certain skin and respiratory infections. The dosage depends on the specific infection you're using it for. The most common side effects are related to the stomach, like nausea, vomiting, and diarrhea. Erythromycin comes in two forms that are taken by mouth: oral tablets and an oral suspension.
Indications for Erythromycin
- Respiratory infections (including upper respiratory tract infection and lower respiratory tract infection)
- Listeria infection
- Skin infections
- Pertussis (whooping cough)
- Diphtheria infection
- Intestinal amebiasis
- Sexually-transmitted infections, STIs (e.g., chlamydia, gonorrhea, syphilis)
- Legionnaires’ Disease
- Prevention of rheumatic fever
Pros and Cons for Erythromycin
Pros
- Treats many types of infections
- Available as a lower-cost generic
- EES is available as an oral tablet or oral suspension
Cons
- Commonly causes nausea, diarrhea, vomiting, and stomach upset
- Interacts with many medications
- Has to be taken multiple times a day
Common Side Effects for Erythromycin
- Nausea
- Vomiting
- Stomach pain
- Diarrhea
- Anorexia
Warnings for Erythromycin
- Liver damage
- Life-threatening changes in your heart rhythm (QT prolongation)
- Syphilis in infants
- Severe diarrhea
- Interactions with other medications
- Worsening of myasthenia gravis
- Intestinal blockage in babies
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