Compare
Dorzolamide vs. Brimonidine

Dorzolamide is an eye drop medication used to treat high pressure in the eye in people with glaucoma or ocular hypertension. The dosage is 1 drop applied directly into the affected eye(s) three times per day. It's available as a generic only as the brand-name medication Trusopt has been discontinued. Dorzolamide is a sulfa medication, so it might not be the best choice if you have a serious sulfa allergy. Side effects include burning or stinging in the eye and a bitter taste in the mouth.

Treatment of high pressure in the eye in people with:

• Ocular hypertension
• Open-angle glaucoma

• Burning or stinging in the eye (33%)
• Bitter taste (25%)
• Bacterial eye infection (10-15%)
• Allergic reaction in the eye (10%)

• Severe allergic reactions
• Risk for eye infection (from contamination)
• Risk for swelling of the cornea

Alphagan P (brimonidine) is a prescription eye drop that helps lower pressure in the eye and treats glaucoma. It's typically applied three times a day. Some common side effects include blurry vision, slight stinging in the eyes, and headaches. Alphagan P (brimonidine) is available as both a brand name and a generic medication.

High pressure in the eye caused by:

• Open-angle glaucoma
• Ocular hypertension

• Dry mouth (up to 30%)
• Red eye (up to 30%)
• Eye burning and stinging (up to 30%)
• Headache (up to 30%)
• Blurry vision (up to 30%)
• Feeling like there's something in your eye (up to 30%)
• Sleepiness (up to 30%)
• Small white patches on the inside of the eyelids (up to 30%)
• Allergic reactions in the eye (up to 30%)
• Itchy eyes (up to 30%)

• Risk of worsening of low blood flow
• Risk of infections (from contamination)
• No soft contact lenses
• Only use in the eye