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Compare Crexont vs. Sinemet

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Crexont (carbidopa / levodopa)
    Carbidopa / levodopa (Sinemet)
  • Crexont (carbidopa / levodopa)
    Carbidopa / levodopa (Sinemet)

  • Summary of Crexont vs. Sinemet

    Summary for Dopa decarboxylase inhibitor / Dopamine replacement
    Prescription only

    Crexont (carbidopa / levodopa) is an extended-release capsule that treats symptoms of Parkinson's disease (PD) in adults. It works to raise dopamine levels in the brain to manage PD symptoms. In general, this medication is taken by mouth, usually 2 to 4 times a day. Your prescriber will adjust the dose based on how well Crexont (carbidopa / levodopa) is working for you. Side effects include nausea and anxiety.

    Summary for Dopa decarboxylase inhibitor / Dopamine replacement
    Prescription only

    Carbidopa / levodopa (Sinemet) is a first-choice option for Parkinson's disease (PD) in adults. It's also used to treat adults with conditions that cause PD symptoms, like shakiness and slowed movement. This medication helps raise and keep dopamine levels high in the brain to help with movement. But it's usually taken multiple times per day to relieve PD symptoms. Immediate-release tablets are available as brand name Sinemet and generic. Extended-release tablets and orally disintegrating tablets are generic only. Side effects can include movement problems, nausea, and possible hallucinations.

  • Indications of Crexont vs. Sinemet

    Indications for
    •Parkinson's disease (PD)
    •Parkinsonism (conditions that cause people to have PD symptoms, including tremors, slowness, and stiffness)
    Indications for
    •Parkinson's disease (PD)
    •Parkinsonism (conditions that cause people to have PD symptoms, like slowness, stiffness, and tremors)

  • Pros and Cons of Crexont vs. Sinemet

    Pros and Const for Dopa decarboxylase inhibitor / Dopamine replacement
    Pros
    •Can provide more "on" time than immediate-release Sinemet (carbidopa / levodopa)
    •Dose can be adjusted based on how the medication is working for you
    •Available in 4 different strengths
    Cons
    •Usually need to take multiple times per day
    •Can make you very sleepy and possibly fall asleep suddenly
    •Might not be a good option for people who have trouble swallowing pills
    Pros and Const for Dopa decarboxylase inhibitor / Dopamine replacement
    Pros
    •First-choice option for treating PD symptoms
    •Available in many forms: immediate-release (IR) tablets, extended-release (ER) tablets, and orally disintegrating tablets (ODTs)
    •Might work within 1 hour
    Cons
    •Usually need to take many times per day to control PD symptoms
    •Can make you very sleepy and possibly fall asleep suddenly
    •Can darken the color of your saliva, sweat, and urine

  • Common Side Effects of Crexont vs. Sinemet

    Common Side Effects for
    •Involuntary movements (dyskinesia, 2-7%)
    •Nausea (4-5%)
    •Anxiety (2-3%)
    •Dizziness (2-3%)
    •Constipation (2%)
    •Headache (1-2%)
    •Vomiting (1-2%)
    •Trouble sleeping (1-2%)
    Common Side Effects for
    •Involuntary movements (dyskinesia or dystonia)
    •Nausea

  • Warnings of Crexont vs. Sinemet

    Common Side Effects for
    •Sleepiness or falling asleep during activities
    •High fevers and confusion with treatment changes
    •Heart problems
    •Hallucinations and changes in behavior and thoughts
    •Difficulty controlling impulsive behavior
    •Low vitamin B6 levels and seizures
    •Stomach bleeding in people who've had a stomach ulcer
    •Rise in eye pressure in people with glaucoma
    Common Side Effects for
    •Sleepiness or falling asleep during activities
    •High fevers and confusion when lowering the dose or stopping too suddenly
    •Hallucinations and changes in behavior and thoughts
    •Difficulty controlling impulsive behavior
    •Risk of depression and thoughts of suicide
    •Low vitamin B6 levels and seizures
    •Caution use in people with a history of heart attack and arrhythmia
    •Caution use in people with a history of stomach ulcers
    •Higher eye pressure in people with glaucoma
    •Caution use in people with phenylketonuria (PKU) - orally disintegrating tablets only

  • Prices with our coupons for Crexont vs. Sinemet

    Learn more about Crexont
    Learn more about Carbidopa / levodopa

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