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Crexont vs. Sinemet

Crexont (carbidopa / levodopa) is an extended-release capsule that treats symptoms of Parkinson's disease (PD) in adults. It works to raise dopamine levels in the brain to manage PD symptoms. In general, this medication is taken by mouth, usually 2 to 4 times a day. Your prescriber will adjust the dose based on how well Crexont (carbidopa / levodopa) is working for you. Side effects include nausea and anxiety.

• Parkinson's disease (PD)
• Parkinsonism (conditions that cause people to have PD symptoms, including tremors, slowness, and stiffness)

• Involuntary movements (dyskinesia, 2-7%)
• Nausea (4-5%)
• Anxiety (2-3%)
• Dizziness (2-3%)
• Constipation (2%)
• Headache (1-2%)
• Vomiting (1-2%)
• Trouble sleeping (1-2%)

• Sleepiness or falling asleep during activities
• High fevers and confusion with treatment changes
• Heart problems
• Hallucinations and changes in behavior and thoughts
• Difficulty controlling impulsive behavior
• Low vitamin B6 levels and seizures
• Stomach bleeding in people who've had a stomach ulcer
• Rise in eye pressure in people with glaucoma

Carbidopa / levodopa (Sinemet) is a first-choice option for Parkinson's disease (PD) in adults. It's also used to treat adults with conditions that cause PD symptoms, like shakiness and slowed movement. This medication helps raise and keep dopamine levels high in the brain to help with movement. But it's usually taken multiple times per day to relieve PD symptoms. Immediate-release tablets are available as brand name Sinemet and generic. Extended-release tablets and orally disintegrating tablets are generic only. Side effects can include movement problems, nausea, and possible hallucinations.

• Parkinson's disease (PD)
• Parkinsonism (conditions that cause people to have PD symptoms, like slowness, stiffness, and tremors)

• Involuntary movements (dyskinesia or dystonia)
• Nausea

• Sleepiness or falling asleep during activities
• High fevers and confusion when lowering the dose or stopping too suddenly
• Hallucinations and changes in behavior and thoughts
• Difficulty controlling impulsive behavior
• Risk of depression and thoughts of suicide
• Low vitamin B6 levels and seizures
• Caution use in people with a history of heart attack and arrhythmia
• Caution use in people with a history of stomach ulcers
• Higher eye pressure in people with glaucoma
• Caution use in people with phenylketonuria (PKU) - orally disintegrating tablets only