Bylvay
(odevixibat)
Get free couponsLivmarli
(maralixibat)
Get free couponsSummary for Bylvay
Bylvay (odevixibat) is a newly approved medication for the treatment of itching in children with a genetic liver condition called progressive familial intrahepatic cholestasis (PFIC). It's taken once per day by mouth, and is available in both capsules and pellets that can be mixed with soft foods.
Indications for Bylvay
- Itching in children 3 months and older with progressive familial intrahepatic cholestasis (PFIC)
Pros and Cons for Bylvay
Pros
- Can be used in children as young as 3 months old
- Taken once per day
- Contents from capsules and pellets can be sprinkled onto food for those who have trouble swallowing
- Dosing can be individualized based on weight
Cons
- Brand name only, which can be expensive
- Needs to be taken with food
- Can cause liver problems, diarrhea, and poor absorption of vitamins A, D, E, and K
Common Side Effects for Bylvay
- Diarrhea (31%)
- Vomiting (17%)
- Liver damage (17%)
- Stomach pain (14%)
Warnings for Bylvay
- Worsening liver problems and liver failure
- Diarrhea
- Low levels of vitamins A, D, E, and K
Summary for Livmarli
Livmarli (maralixibat) is FDA approved to help with itching caused by liver problems (cholestatic pruritis) from certain genetic conditions. It's for adults and children with Alagille syndrome (ALGS). This medication is also for people 1 year and older with progressive familial intrahepatic cholestasis (PFIC). It works as an ileal bile acid transporter (IBAT) inhibitor. Livmarli (maralixibat) comes as a tablet and a liquid. You take each dose by mouth on an empty stomach. Common side effects include diarrhea and stomach pain.
Indications for Livmarli
- Itching caused by liver problems (cholestatic pruritis) from:
- Alagille syndrome (ALGS) in people 3 months of age and older
- Progressive familial intrahepatic cholestasis (PFIC) in people 1 year of age and older
Pros and Cons for Livmarli
Pros
- Works well to help improve itchiness from ALGS and PFIC
- Approved for both adults and children with ALGS or PFIC
- Available as a tablet and a grape-flavored liquid
Cons
- Need to take 30 minutes before a meal
- Might take several weeks to start working
- Can cause stomach upset and poor absorption of certain vitamins (vitamins A, D, E, and K)
Common Side Effects for Livmarli
ALGS:
- Diarrhea (56%)
- Stomach pain (54%)
- Vomiting (41%)
- Low vitamin A, D, E, and K levels (26%)
- Higher liver enzyme levels (19%)
PFIC:
- Diarrhea (57%)
- Stomach pain (28%)
- Higher liver enzyme levels (17%)
Warnings for Livmarli
- Liver damage
- Stomach upset
- Low vitamin A, D, E, and K
- Risk of propylene glycol toxicity in young children
Prices with our coupons for Bylvay vs. Livmarli
Browse medications by letter
Show AllBrowse prescription and over-the-counter medications from A to Z, compare drug prices, and start saving.
