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Compare Bylvay vs. Livmarli

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Bylvay (odevixibat)
    Livmarli (maralixibat)
  • Bylvay (odevixibat)
    Livmarli (maralixibat)

  • Summary of Bylvay vs. Livmarli

    Summary for Ileal bile acid transporter (IBAT) inhibitor
    Prescription only

    Bylvay (odevixibat) is a newly approved medication for the treatment of itching in children with a genetic liver condition called progressive familial intrahepatic cholestasis (PFIC). It's taken once per day by mouth, and is available in both capsules and pellets that can be mixed with soft foods.

    Summary for Ileal bile acid transporter (IBAT) inhibitor
    Prescription only

    Livmarli (maralixibat) is FDA approved to help with itching caused by liver problems (cholestatic pruritis) from certain genetic conditions. It's for adults and children with Alagille syndrome (ALGS). This medication is also for people 1 year and older with progressive familial intrahepatic cholestasis (PFIC). It works as an ileal bile acid transporter (IBAT) inhibitor. Livmarli (maralixibat) comes as a tablet and a liquid. You take each dose by mouth on an empty stomach. Common side effects include diarrhea and stomach pain.

  • Indications of Bylvay vs. Livmarli

    Indications for
    •Itching in children 3 months and older with progressive familial intrahepatic cholestasis (PFIC)
    Indications for
    •Itching caused by liver problems (cholestatic pruritis) from:
    •Alagille syndrome (ALGS) in people 3 months of age and older
    •Progressive familial intrahepatic cholestasis (PFIC) in people 1 year of age and older

  • Pros and Cons of Bylvay vs. Livmarli

    Pros and Const for Ileal bile acid transporter (IBAT) inhibitor
    Pros
    •Can be used in children as young as 3 months old
    •Taken once per day
    •Contents from capsules and pellets can be sprinkled onto food for those who have trouble swallowing
    •Dosing can be individualized based on weight
    Cons
    •Brand name only, which can be expensive
    •Needs to be taken with food
    •Can cause liver problems, diarrhea, and poor absorption of vitamins A, D, E, and K
    Pros and Const for Ileal bile acid transporter (IBAT) inhibitor
    Pros
    •Works well to help improve itchiness from ALGS and PFIC
    •Approved for both adults and children with ALGS or PFIC
    •Available as a tablet and a grape-flavored liquid
    Cons
    •Need to take 30 minutes before a meal
    •Might take several weeks to start working
    •Can cause stomach upset and poor absorption of certain vitamins (vitamins A, D, E, and K)

  • Common Side Effects of Bylvay vs. Livmarli

    Common Side Effects for
    •Diarrhea (31%)
    •Vomiting (17%)
    •Liver damage (17%)
    •Stomach pain (14%)
    Common Side Effects for

    ALGS:

    •Diarrhea (56%)
    •Stomach pain (54%)
    •Vomiting (41%)
    •Low vitamin A, D, E, and K levels (26%)
    •Higher liver enzyme levels (19%)

    PFIC:

    •Diarrhea (57%)
    •Stomach pain (28%)
    •Higher liver enzyme levels (17%)

  • Warnings of Bylvay vs. Livmarli

    Common Side Effects for
    •Worsening liver problems and liver failure
    •Diarrhea
    •Low levels of vitamins A, D, E, and K
    Common Side Effects for
    •Liver damage
    •Stomach upset
    •Low vitamin A, D, E, and K
    •Risk of propylene glycol toxicity in young children

  • Prices with our coupons for Bylvay vs. Livmarli

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