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Clindamycin/Benzoyl Peroxide

Clindamycin/Benzoyl Peroxide Side Effects

Robert Chad Hakim, PharmD, BCCCPKristianne Hannemann, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Kristianne Hannemann, PharmD
Last reviewed on November 14, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Neuac:

  • Mild skin redness (26%)
  • Mild skin peeling (17%)
  • Mild skin dryness (15%)
  • Mild skin burning (5%)

Acanya:

  • Mild skin redness (25%)
  • Mild skin scaling (18%)
  • Mild skin itching (15%)
  • Mild skin burning (8%)

Clindamycin 1% / benzoyl peroxide 5%:

  • Dryness (12%)

Less Common Side Effects

  • Stinging
  • Sunburn

Clindamycin/Benzoyl Peroxide serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Inflammation of your large intestine: diarrhea that doesn't go away (especially if it's bloody), severe stomach cramps
  • Serious allergic reaction: hives; trouble breathing; itching; swelling of your face, eyes, lips, tongue, or throat
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When do Clindamycin/Benzoyl Peroxide possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Skin dryness
Skin redness
Skin peeling
Skin burning
Skin itching
Skin shedding

Source: DailyMed

The following Clindamycin/Benzoyl Peroxide side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Dry skin

Less common

Burning, itching, redness, skin rash, swelling, or soreness at the application site

flushing or redness of the skin

peeling

sunburn

unusually warm skin

Incidence not known

Cough

difficulty with swallowing

dizziness

fast heartbeat

hives or skin rash

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

tightness in the chest

unusual tiredness or weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Kristianne Hannemann, PharmD, is a licensed pharmacist in California. She has been a retail pharmacy manager and staff pharmacist for over 7 years and has contributed drug information content to different health companies.

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