What should I watch for?
This medicine does not prevent heart attack or stroke. In fact, this medicine may increase the chance of a heart attack or stroke. The chance may increase with longer use of this medicine and in people who have heart disease. If you take aspirin to prevent heart attack or stroke, talk with your doctor or health care professional.
Do not take medicines such as ibuprofen and naproxen with this medicine. Side effects such as stomach upset, nausea, or ulcers may be more likely to occur. Many medicines available without a prescription should not be taken with this medicine.
This medicine can cause ulcers and bleeding in the stomach and intestines at any time during treatment. Do not smoke cigarettes or drink alcohol. These increase irritation to your stomach and can make it more susceptible to damage from this medicine. Ulcers and bleeding can happen without warning symptoms and can cause death.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
This medicine can cause you to bleed more easily. Try to avoid damage to your teeth and gums when you brush or floss your teeth.
If you are female, do not use this medicine if you are pregnant. Do not get pregnant while taking this medicine and for at least one month (one full menstrual cycle) after stopping this medicine. If you can have children, use a reliable form of birth control while taking this medicine. Talk to your doctor about birth control options. If you become pregnant, think you are pregnant, or want to become pregnant, immediately call your doctor for advice.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Black, tarry stools
bleeding or crusting sores on the lips
blood in the urine or stools
bruises or red spots on the skin
cough or hoarseness
fever with or without chills
general feeling of illness
heartburn or indigestion
increased heart rate
increased weight gain
itching of the skin
large, flat, blue or purplish patches on the skin
lightheadedness or dizziness
lower back or side pain
painful or difficult urination
seeing, hearing, or feeling things that are not there
severe liver reactions
severe stomach pain, cramping, or burning
sores, ulcers, or white spots on the lips or in the mouth
stiff neck or back
sudden decrease in the amount of urine
swelling or tenderness in the upper stomach
swelling of the face, fingers, feet, or lower legs
troubled breathing, tightness in the chest
unusual bleeding or bruising
unusual tiredness or weakness
vomiting of material that looks like coffee grounds
yellow eyes or skin
Changes in facial skin color
fast or irregular breathing
puffiness or swelling of the eyelids or around the eyes
Get emergency help immediately if any of the following symptoms of overdose occur:
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.