Telmisartan (Micardis) is an angiotensin II receptor blocker (ARB). It's a prescription medication used to treat high blood pressure in adults. Telmisartan (Micardis) is also used to lower the risk of death or heart attack in certain people with heart problems. This medication is taken by mouth, typically once a day. Side effects aren't common, but people taking telmisartan (Micardis) have reported ones like upper respiratory infection and back pain.
Lowering the risk of death, stroke, or heart attack in certain adults 55 years or older with a history of heart problems (e.g., coronary artery disease)
Telmisartan (Micardis) is an angiotensin II receptor blocker (ARB). It works by blocking a hormone called angiotensin II. The main role of angiotensin II is to narrow your blood vessels. This then raises your blood pressure and causes your heart to work harder to pump out blood to the rest of your body. So by blocking this hormone, telmisartan (Micardis) relaxes your blood vessels, which lowers your blood pressure and eases the stress on your heart.
Source: DailyMed
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Rare
Changes in vision
dizziness, lightheadedness, or fainting
fast heartbeat
large hives
painful urination or changes in urinary frequency
swelling in the hands, lower legs, and feet
Incidence not known
Blurred vision
chest pain or discomfort
confusion
dark-colored urine
decreased urine output
dilated neck veins
extreme fatigue
flushing
hives or welts
hoarseness
irregular breathing
irritation
joint pain, stiffness, or swelling
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
muscle cramps or stiffness
numbness or tingling in the hands, feet, or lips
pain or discomfort in the arms, jaw, back, or neck
pounding in the ears
rash
redness of the skin
slow, fast, or irregular heartbeat
sweating
swelling of the eyelids, face, or lips
tightness in the chest
trouble breathing or swallowing
trouble with speaking or walking
trouble with thinking
unusual tiredness or weakness
unusually warm skin
weakness or heaviness of the legs
weakness, numbness, or tingling in the arms or legs
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Abdominal or stomach pain
back pain
changes in appetite
ear pain or hearing problems
general tiredness or weakness
headache
increased sweating
muscle pain or spasm
nervousness
runny or stuffy nose
Incidence not known
Acid or sour stomach
belching
decreased interest in sexual intercourse
difficulty with moving
inability to have or keep an erection
indigestion
joint pain
lack or loss of strength
leg cramps
loss in sexual ability, desire, drive, or performance
muscle aching
stomach discomfort or upset
swelling
weakness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Available as a lower-cost generic medication
Typically taken once a day
Lowers the risk of heart attack or death due to heart problems in people with CAD
Less likely to cause dry cough compared to ACE inhibitors
Can’t take while pregnant
Might require regular blood work and lab tests to make sure your kidneys are functioning normally
Not safe for use in children
Can take up to 4 weeks to see the full effect on high blood pressure
You can keep track of how well telmisartan (Micardis) is working to control your blood pressure by checking your blood pressure regularly at home. Write down your blood pressure readings, and bring them to your appointments with your primary care provider so you can discuss how well telmisartan (Micardis) is working for you.
Telmisartan (Micardis) works to lower your blood pressure, but this can cause dizziness and lightheadedness. You're more likely to feel dizzy or lightheaded during the first few days and if you're suddenly standing up from a sitting or lying down position. Make sure to get up slowly. Tell your primary care provider if you experience fainting or dizziness while taking this medication.
Mark your calendar with your appointments to see your primary care provider and to get any blood work done when you take telmisartan (Micardis). Your primary care provider might order tests to check your potassium levels and kidney health during treatment. Based on your lab results and your blood pressure readings, they might change your dose to make sure the medication is safe and working well for you.
Remember to drink enough water to stay hydrated while you're taking telmisartan (Micardis), especially on hot days or after exercising. Dehydration can put you at risk for very low blood pressure, dizziness, and falls. In addition, not having enough fluids in your body might raise your risk of kidney damage during treatment with this medication.
Don't take telmisartan (Micardis) if you're pregnant or nursing since it can cause harm to your baby. If you're pregnant or thinking of getting pregnant during treatment, contact your primary care provider right away. Your primary care provider might prescribe you a different medication that's safer during pregnancy or suggest lifestyle changes.
Telmisartan (Micardis) can interact with many medications. Let your care team know what medications you're taking, including over-the-counter products and supplements, before you start telmisartan (Micardis). Talk with your care team if you have any questions about interactions with this medication.
Avoid taking telmisartan (Micardis) with angiotensin-converting enzyme (ACE) inhibitors, such as ramipril. Both of these medications work similarly, so taking them together can worsen your kidney problems or cause dangerously low blood pressure.
Telmisartan (Micardis) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Taking telmisartan (Micardis) during the second and third trimesters of pregnancy might raise the risk for birth defects, such as kidney problems. Sometimes, this can be fatal to the unborn baby. Because of this potential risk, if you find out that you're pregnant while you're taking telmisartan (Micardis), stop and let your primary care provider know right away. If you're pregnant or are planning to become pregnant, discuss safer treatment options with your care team.
Risk factors: Low fluids in the body (e.g., dehydration) | Low salt levels in your body | People on dialysis | Taking diuretics
Sometimes, taking telmisartan (Micardis) can cause your blood pressure to drop too much. This can cause you to feel dizzy, tired, or lightheaded. Low blood pressure is more common in the first 2 weeks of starting telmisartan (Micardis) and when your dose goes up. Make sure to stay well-hydrated during treatment. Don't get up suddenly from a sitting or lying down position, since this can cause your blood pressure to drop quickly. If you frequently feel dizzy, lightheaded, faint, tired, or confused while taking telmisartan (Micardis), let your primary care provider know.
Risk factors: Severe heart failure | Kidney problems | Taking diuretics
Telmisartan (Micardis) can usually improve blood flow to the kidneys, which is good for people with high blood pressure and chronic kidney disease (CKD). But in some cases, telmisartan (Micardis) can make kidney problems worse. The risk is higher for people who have certain medical conditions, such as blockage of the kidney artery or severe heart failure. As a result, your primary care provider might order lab tests during treatment to make sure your kidneys are healthy and working properly. Let your primary care provider know if you're urinating less often than usual, feeling tired, nauseous, or have chills. These can be symptoms of kidney damage.
Risk factors: Diabetes | Kidney problems | Taking other medications that also raise potassium
Very rarely, telmisartan (Micardis) can raise the amount of potassium in your body, which can be dangerous. Your risk of developing high potassium is greater if you have diabetes, kidney problems, or are taking other medications that also raise potassium levels. For this reason, make sure your primary care provider knows your full medical history and what medications you're taking before starting telmisartan (Micardis). If you experience signs of high potassium, such as nausea, muscle weakness, or abnormal heartbeat, tell your provider right away.
Risk factor: History of liver problems
In some rare cases, people with a history of liver problems (e.g., blocked bile duct) can end up with a higher amount of telmisartan (Micardis) in their body. This can lead to higher risk of side effects, such as low blood pressure and kidney problems. Make sure to let your care team know if you've a history of liver problems. Your primary care provider can start you at a lower dose of the medication to make sure it's safe for you.
High blood pressure: The typical starting dose is 40 mg by mouth once a day. Your prescriber will adjust your dose according to your blood pressure. The usual dosage range is 20 mg to 80 mg once a day.
Lowering the risk of heart attack and stroke: The typical dose is 80 mg by mouth once daily.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Taking aliskiren (Tekturna) and you also have diabetes
Lowering the risk of death, stroke, or heart attack in certain adults 55 years or older with a history of heart problems (e.g., coronary artery disease)
Lower the risk of stroke in people with high blood pressure who have a thickened heart (left ventricular hypertrophy)
Slow down the worsening of kidney problems in people with Type 2 diabetes and high blood pressure
High blood pressure in adults and children
Lower the risk of worsening heart failure in adults
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Glenmark Pharmaceuticals Inc., USA. (2024). TELMISARTAN tablet [package insert]. DailyMed.
National Kidney Foundation. (2023). ACE Inhibitors and ARBs.
Shah, R., et al. (2023). Cholestatic jaundice. StatPearls.
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