Lidocaine 5% patch (Lidoderm) is a prescription medication used to relieve nerve pain caused by a shingles infection, also called postherpetic neuralgia (PHN). It's a local anesthetic that works by numbing your nerves to help reduce pain. You apply the patch directly to the painful area of your skin once a day, and it can be worn for up to 12 hours in a 24-hour period. Common side effects include temporary skin irritation, redness, and a mild burning sensation where the patch is applied.
Nerve pain caused by shingles (postherpetic neuralgia)
Lidocaine 5% patch (Lidoderm) is a local anesthetic, which means it works by numbing the area where it’s applied. It blocks pain signals from the nerves in your skin so they don’t reach your brain. This helps relieve pain in a specific spot without affecting the rest of your body.
Source: DailyMed
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
More common
Blurred vision or other changes in vision
burning feeling at site of application
redness of the white part of eyes or inside of eyelids
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Headache
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Works directly on the skin
Generally well-tolerated with few side effects
Can cut patches to fit the area of pain
Commonly causes skin irritation
Must avoid contact with water wearing the patch
Might interact with many medications
Always wash your hands after applying lidocaine 5% patch (Lidoderm). This gets rid of any medication left on your fingers and helps prevent it from getting in your eyes, which can cause burning or irritation.
Don't apply lidocaine 5% patch (Lidoderm) to areas of your skin with open cuts or wounds. This might affect how your skin absorbs the medication and can lead to more side effects.
Lidocaine 5% patch (Lidoderm) might not stick to skin well if it gets wet. Avoid bathing, showering, or swimming while wearing the patch.
You can cut lidocaine 5% patch (Lidoderm) into smaller pieces to fit the painful area. This won't affect how the medication works.
Don't use heat over lidocaine 5% patch (Lidoderm), like heating pads or electric blankets. This can cause your body to absorb too much medication, but regular clothing is okay to wear over it.
Avoid using other products with lidocaine (like OTC patches or creams, ointments, and gels) while using lidocaine 5% patch (Lidoderm) at the same time. Doing so raises your risk of side effects.
Lidocaine 5% patch (Lidoderm) can interact with certain medications and raise your risk of methemoglobinemia, a rare condition that affects oxygen in your blood. Tell your prescriber if you notice symptoms like pale or gray skin, shortness of breath, fast heartbeat, or dizziness. Share a full list of your medications with your prescriber before using this patch.
Mild skin irritation is common with lidocaine 5% patch (Lidoderm) and generally goes away within a few minutes to hours. If you feel itching, burning, or dryness, remove the patch and wait for the symptoms to go away before using it again. Tell your prescriber if the irritation doesn’t go away or gets worse.
Throw away each lidocaine 5% patch (Lidoderm) after one use. Fold it in half with the sticky sides together before throwing it away to keep others — especially kids or pets — from getting exposed to leftover medication.
Store lidocaine 5% patch (Lidoderm) safely out of reach of children. If you think a child has touched or had contact with a patch, call Poison Control at 1-800-222-1222 right away.
Lidocaine 5% patch (Lidoderm) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
*Risk factors: History of methemoglobinemia | History of low glucose-6-phosphate dehydrogenase (G6PD) | Heart or lung problems | Age 6 months or younger | Exposure to other oxidizing agents, such as chlorine and hydrogen peroxide | Taking other medications that raise the risk for methemoglobinemia *
While rare, local anesthetics like lidocaine 5% patch (Lidoderm) can cause methemoglobinemia, a serious blood problem where your red blood cells can't carry enough oxygen throughout your body. The risk is higher in people with glucose-6-phosphate dehydrogenase (G6PD) deficiency, a history of methemoglobinemia, heart or lung problems, and in infants under 6 months. Be careful using lidocaine 5% patch (Lidoderm) patches if you're around oxidizing chemicals like chlorine or hydrogen peroxide, which might be present in cleaning supplies or hair dye.
Symptoms can show up right away or a few hours later, and can include gray, blue, or pale-colored skin. If not treated quickly, methemoglobinemia can lead to seizures, irregular heartbeat, coma, or even death. If you notice any of these symptoms, stop using lidocaine 5% patch (Lidoderm) and get emergency medical help right away.
Risk factors: Using heating pad or electric blanket on skin | Applying the patch to red, irritated, or broken skin | Leaving the patch on for more than 12 hours | Using more patches than recommended | Liver problems | Kidney problems
Your body can absorb too much lidocaine from lidocaine 5% patch (Lidoderm) if you use more patches than recommended or leave them on too long. This can also happen if you put the patches on broken skin or use a heating pad over them. Absorbing too much lidocaine is dangerous and can cause serious side effects. If you notice numbness around your mouth, tingling in your tongue, dizziness, ringing in your ears, or blurred vision, remove the patch and get medical help immediately.
Risk factors: Not storing or throwing away lidocaine 5% patch (Lidoderm) patches correctly
When you’re done using a lidocaine 5% patch (Lidoderm), fold it in half with the sticky sides together before throwing it away. This helps keep the medication from getting on a child or pet if they find it. Even a used patch can still contain a lot of lidocaine, and if a child or pet chews or swallows it, it could cause serious harm. Always store and throw the patches away safely and out of reach. If you think a child or pet has chewed or eaten a patch, call 911 or Poison Control at 1-800-222-1222 right away.
Dosage | Quantity | Price as low as | Price per unit |
---|---|---|---|
5% | 30 patches | $811.06 | $27.04 |
The typical dose is to apply up to 3 patches to the painful area of skin once a day for 12 hours during a 24-hour period. This means you can leave the patch(es) on for up to 12 hours, but you should take a 12-hour break before applying on a new patch.
GoodRx has partnered with PatientsLikeMe to provide reviews on the different aspects of Lidocaine 5% patch (Lidoderm).
Learn more about the effectiveness of Lidocaine 5% patch (Lidoderm) based on real life experiences.
Based on 12 people taking this medication
3.4
3.1
1.9
3.1
3.8
5.0
Severity of side effects
Based on 132 people taking this medication
0%
50%
100%
Rash or skin problems
4%
Application site itching
2%
Burning sensation in skin
2%
Bruising
1%
Elevated blood pressure
1%
Reasons people stopped taking Lidocaine 5% patch (Lidoderm)
Based on 108 people who have taken this medication
Did not seem to work
41%
Expense
17%
Course of treatment ended
16%
Other
11%
Change in health plan coverage
7%
Doctor's advice
4%
Side effects too severe
4%
Personal research
3%
How long people take Lidocaine 5% patch (Lidoderm)
Based on 388 people taking this medication
0%
50%
100%
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Nerve pain caused by shingles (postherpetic neuralgia)
Nerve pain caused by shingles (postherpetic neuralgia)
Treatment of shingles-related nerve pain (postherpetic neuralgia)
Treatment of diabetes-related nerve pain in the feet (diabetic peripheral neuropathy)
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Medcore LLC. (2024). LIDOCAINE 5% PATCH- lidocaine 5% patch. DailyMed.
MedlinePlus. (n.d.). Glucose-6-phosphate dehydrogenase deficiency.
MedlinePlus. (2024). Methemoglobinemia.
Rowbotham M. C., et al. (1996). Lidocaine patch: double-blind controlled study of a new treatment method for post-herpetic neuralgia. Pain.
Torp, K. D., et al. (2022). Lidocaine Toxicity. StatPearls.
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