Compare Praluent vs. Repatha
Head-to-head comparisons of medication uses, side effects, warnings, and more.
- Praluent (alirocumab)Repatha (evolocumab)
- Praluent (alirocumab)Repatha (evolocumab)
Summary of Praluent vs. Repatha
Summary for PCSK9 inhibitorPrescription onlyPraluent (alirocumab), is a PCSK9 inhibitor used to treat high cholesterol in certain adults and children, including those with a genetic condition called familial hypercholesterolemia. The medication also helps lower the risk of heart attack, stroke, and hospitalization for chest pain in adults with heart disease. Praluent (alirocumab) is injected under the skin in the thigh, stomach, or upper arm every 2 weeks or 4 weeks, depending on your dose. Common side effects include injection-site reactions, flu or flu-like symptoms (e.g. sneezing, coughing, runny nose), and diarrhea.
Summary for PCSK9 inhibitorPrescription onlyRepatha (evolocumab) is a PCSK9 inhibitor that's used to treat high cholesterol in adults and certain children. It also helps lower the risk of heart attack and stroke for adults with heart disease. Repatha (evolocumab) is typically used when you're having trouble managing cholesterol levels with a heart-healthy diet or with other cholesterol medications (like statins). Repatha (evolocumab) is an injection under the skin that's given either once every 2 weeks or once every month. Repatha (evolocumab) side effects can include discomfort near the injection site and cold- or flu-like symptoms.
Indications of Praluent vs. Repatha
Indications for•Lower the risk of heart attack, stroke, and hospitalization for chest pain (angina) in adults with heart disease•High cholesterol (including heterozygous familial hypercholesterolemia (HeFH)) in adults, alone or with diet and other cholesterol-lowering medications•Homozygous familial hypercholesterolemia (HoFH) in adults, along with other cholesterol-lowering medications•Heterozygous familial hypercholesterolemia (HeFH) in children ages 8 and older, along with diet and other cholesterol-lowering medicationsIndications for•High cholesterol in adults•Inherited condition causing extremely high cholesterol (heterozygous and homozygous familial hypercholesterolemia) in people aged 10 years and older•Lower the risk of heart attack, stroke, and the need for heart procedures (like stent placement) in adults with known heart diseasePros and Cons of Praluent vs. Repatha
Pros and Const for PCSK9 inhibitorPros•Lowers LDL ("bad") cholesterol by about 50% to 60%•Reduces the risk of heart problems in adults with heart disease•Used alone or with other cholesterol-lowering medications•Given either every 2 or 4 weeksCons•Must be injected under the skin•Side effects include injection-site reactions, flu, and diarrhea•Potential for serious allergic reactions•Not known if safe during pregnancy or breastfeedingPros and Const for PCSK9 inhibitorPros•Only taken either every 2 weeks or once every month•Can help lower your cholesterol levels if other medications haven't worked well enough•Can use for children as young as 10 years old with familial hypercholesterolemia•Available in multiple forms (prefilled syringe, prefilled autoinjector, or single-use on-body infusor)Cons•Only available as an injection•Long-term side effects aren't fully known (compared to statins)•No lower-cost generic available (brand-name medication only)Common Side Effects of Praluent vs. Repatha
Common Side Effects forCommon Side Effects for•Common cold symptoms (11%)•Flu-like symptoms (8%)•Back pain (6%)•Redness, pain, or bruising at the injection site (6%)Warnings of Praluent vs. Repatha
Common Side Effects for•Serious allergic reactionCommon Side Effects for•Allergic reactionPrices with our coupons for Praluent vs. Repatha
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