Furosemide (Lasix) and spironolactone (Aldactone) are both diuretics, or "water pills," used to treat conditions like swelling due to heart, liver, or kidney problems, and high blood pressure. However, they belong to different classes of diuretics. Furosemide is a loop diuretic, while spironolactone is a potassium-sparing diuretic. Furosemide is available as a tablet or oral solution and is typically taken once or twice daily. Spironolactone comes in tablet form and as an oral suspension, with dosing varying based on the condition being treated. Both medications are available as a generic. Common side effects of furosemide include increased urination, dizziness, and sun sensitivity, while spironolactone can cause dizziness, breast tenderness, and changes in libido. Furosemide can lead to low potassium levels, whereas spironolactone can cause high potassium levels, so it's important to monitor your electrolytes with both medications.