Key takeaways:
Methamphetamine — also called meth or crystal meth — is an addictive stimulant that has powerful and harmful effects on the brain and body.
Meth is addictive and can lead to a stimulant use disorder. Someone may prioritize the substance before other things in their lives, including their relationships, work, and health.
Other signs of meth addiction include psychosis, aggression, and withdrawal.
Methamphetamine goes by many names, including meth and crystal meth. And its misuse is a serious issue in the U.S. Nearly 1.8 million people in the U.S. have a methamphetamine use disorder. And millions more have used this addictive substance at least once in their life. It’s among the most misused drugs across the globe.
Recognizing the signs of meth addiction can help you take steps to get help for yourself or a loved one. We’ll cover the physical, behavioral, and emotional symptoms that can suggest that someone is experiencing meth use disorder.
Methamphetamine is an addictive stimulant. Stimulant drugs speed up your body’s functions, so they increase your mental alertness, focus, and energy as well as decreasing appetite. But there are also more serious and dangerous symptoms. The powerful stimulant effects make meth overdose a real danger.
Meth can come in the form of a powder or pill. In 2005, the U.S. put restrictions on the chemicals used to make meth, including pseudoephedrine. But meth can be made from a wide range of chemicals, and some of these are both hazardous and easy to access. Meth can contain acetone, anhydrous ammonia (fertilizer), and ether. The range of chemicals used to make meth present barriers to limiting its production.
Meth triggers the release of large amounts of dopamine in the brain. Dopamine is a chemical in the body that affects motivation, pleasure, and movement.
Dopamine also plays a role in the brain’s “reward response.” When you do something that brings you pleasure, your brain releases dopamine, which makes you feel good. This is why some scientists call it a “teaching” chemical. Dopamine likely contributes to why people repeat behaviors and activities that bring pleasure.
Get help for substance misuse. There are options for treatment and support to help you or a loved one.
How to help someone else: Meth is an addictive stimulant that can disrupt many aspects of someone’s life. Here are ways to help someone with a meth addiction.
Signs of a meth overdose: A meth overdose can be a life-threatening situation. Here’s what to do.
And this helps explain why meth is addictive. People who use meth experience a euphoric and energizing sensation that can lead to repeated use and addiction.
A stimulant use disorder is a condition where someone continues to misuse a stimulant drug — like meth — even though it leads to harmful consequences in their life. Someone experiencing meth addiction may show symptoms such as:
Taking larger amounts of meth or taking meth for a longer period of time than planned
Trying to cut down or quit without success
Giving up activities that they once valued due to meth
Being unable to keep up with responsibilities at home, work, or school
Spending a lot of time getting, using, or recovering from meth
Using meth even when it creates problems in work and social life
Experiencing cravings for meth
Using meth in risky situations
Using meth despite it causing or worsening physical or mental health problems
Needing more meth to feel the same effects over time (tolerance)
Experiencing withdrawal
Long-term meth use can cause physical changes as well as changes to the dopamine system in the brain. Over time, people who use meth may develop problems with learning, memory, and coordination.
Beyond the symptoms of stimulant use disorder we listed above, people who repeatedly use meth over time may experience:
“Meth mouth,” which can include facial changes, dental problems, and jaw pain
Skin sores, which can occur from excessive scratching
Weight loss
Sleeping problems
Paranoia, or extreme and unreasonable distrust of others
Irritability
Confusion
Memory problems
A study of about 34,000 people in Utah found that those who used meth were at increased risk of developing Parkinson’s disease compared to those who didn’t use drugs.
Some of the effects of meth on the brain may improve after 1 year of abstinence (not using). But more research is needed to understand the long-term effects of meth use.
Meth is a powerful and fast-acting substance that can have notable effects on someone’s behavior. Someone who uses meth may be:
Unpredictable
Easily annoyed
Aggressive or violent
Changes in behavior often depend on whether someone is under the influence of meth or is recovering from use. While intoxicated, a person may show a range of moods and behaviors, from energetic and euphoric to restless. As the effects of meth lessen, someone may seem more tired, irritable, or depressed.
People who use meth over a long period of time are also at risk of developing psychosis. These symptoms may continue for months or possibly years after a person stops using meth. This can include symptoms like:
Hallucinations: seeing or hearing things that are not really there
Delusions: rigid beliefs that don’t line up with reality
Paranoia: extreme and unreasonable distrust of others
When someone stops using meth, they may experience withdrawal symptoms. Withdrawal is a sign of physical dependence, which means that the body has become reliant on a substance. Withdrawal is also one of the symptoms of stimulant use disorder.
Signs of meth withdrawal include:
Depression
Anxiety
Irritability
Paranoid thoughts
Changes in sleeping patterns
Low energy
Increased appetite
Trouble concentrating
Cravings
Meth withdrawal looks different from meth intoxication. People who frequently use meth may “binge and crash,” a pattern where they use meth over and over again for a period of time until they crash and stop. Meth withdrawal may set in during the crash period.
If you’re worried about a loved one’s meth addiction, there are ways to help. Clear and direct communication are key parts of strong relationships and getting someone help. But keep in mind that change can take time and isn’t something that can be forced.
You can help your loved one find help and get treatment by contacting the National Helpline from the Substance Abuse and Mental Health Services Administration (SAMHSA) at 1-800-662-HELP (4357), which helps people find treatment programs and healthcare professionals.
You can also suggest that they attend one of the following support groups:
Methamphetamine (meth) is an addictive substance that causes changes to the body and brain. People who are under the influence of meth or are going through withdrawal may show changes in their appearance, mood, and behavior.
Over time, meth use can lead to misuse that causes harmful consequences in someone’s life and health. If you’re concerned that a loved one has a substance use disorder, try to express your concerns directly and to listen to their concerns with empathy. There are resources and treatments that can help.
Bromberg-Martin, E. S., et al. (2010). Dopamine in motivational control: Rewarding, aversive, and alerting. Neuron.
Curtain, K., et al. (2015). Methamphetamine/amphetamine abuse and risk of Parkinson's disease in Utah: A population-based assessment. Drug and Alcohol Dependence.
Drug Enforcement Administration. (2020). Amphetamines.
Glasner-Edwards, S., et al. (2014). Methamphetamine psychosis: Epidemiology and management. CNS Drugs.
National Institute on Drug Abuse. (2021). How is methamphetamine manufactured?
National Institute on Drug Abuse. (2021). How is methamphetamine misused?
National Institute on Drug Abuse. (2021). What are the immediate (short-term) effects of methamphetamine misuse?
National Institute on Drug Abuse. (2022). What are the long-term effects of methamphetamine misuse?
National Institute on Drug Abuse. (2024). The science of drug use and addiction: The basics.
Pabst, A. et al. (2017). Meth mouth — A growing epidemic in dentistry? Dentistry Journal.
Substance Abuse and Mental Health Services Administration. (2015). TIP 45: Detoxification and substance abuse treatment.
Substance Abuse and Mental Health Services Administration. (2023). Know the risks of meth.
Substance Abuse and Mental Health Services Administration. (2024). Key substance use and mental health indicators in the United States: Results from the 2023 National Survey on Drug Use and Health.
If you or someone you know struggles with substance use, help is available. Call SAMHSA’s National Helpline at 1-800-662-4357 to learn about resources in your area.