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Mirvaso vs. Rhofade

Brimonidine (Mirvaso) is a topical gel used to treat adults with facial redness from rosacea that doesn't go away. It's only available with a prescription and belongs to a class of medications called alpha-2 agonist. The gel is applied directly to the face once per day. Side effects are rare but can include skin flushing and a burning sensation. Some people might also experience rebound erythema, where their facial redness worsens after starting the medication.

• Facial redness caused by rosacea in adults

• Redness (4%)
• Flushing (3%)
• Burning sensation (2%)

• Worsening blood flow problems
• Risk of low blood pressure
• Flushing and skin color changes

Rhofade (oxymetazoline) is an alpha-1 receptor agonist. It contains oxymetazoline 1% topical cream and is used to treat facial redness in adults with rosacea. Rhofade (oxymetazoline) is applied to the face once per day. Most people don't experience any side effects from Rhofade (oxymetazoline). But those who do report have reported irritation or rash at the application site. Rhofade (oxymetazoline) is prescription-only and not available as a generic.

• Facial redness caused by rosacea in adults

• Irritation or rash at the application site (2%)

• Changes in blood pressure
• Worsening blood flow problems
• Glaucoma